MK4MDD

Gene Report

Basic Information
Approved Symbol DTNBP1
Approved Name dystrobrevin binding protein 1
Symbol Alias Dysbindin, My031, HPS7, DBND, BLOC1S8
Name Alias "dysbindin-1", "biogenesis of lysosomal organelles complex-1, subunit 8"
Location 6p22.3
Position chr6:15663101-15663289 (-)
External Links Entrez Gene: 84062
Ensembl: ENSG00000047579
UCSC: uc003nbm.3
HGNC ID: 17328
No. of Studies (Positive/Negative) 2(1/1) Help
Type Literature-origin

Positive relationships between DTNBP1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
DTNBP1 Kim, 2008 patients and normal controls P-value=0.0007 Haplotype analyses revealed a significant association with M...... Haplotype analyses revealed a significant association with MDD (p=0.0007, protective A-C-T-A and A-C-C-C haplotypes), in particular the effect was due to the rs760761 (C/T) and rs2619522 (A/C) haplotype (p=0.000026). More...

Positive relationships between DTNBP1 and other components at different levels (count: 0) Help
Positive relationship network of DTNBP1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between DTNBP1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
DTNBP1 Zill P, 2004 Patients and nomal controls Applying single SNP evaluation, as well as haplotype analysi...... Applying single SNP evaluation, as well as haplotype analysis we could not detect an association between the dysbindin polymorphisms and major depression or the response to antidepressant treatment. More...

Negative relationships between DTNBP1 and other components at different levels (count: 0) Help
DTNBP1 related SNPs in MK4MDD (count: 0)
DTNBP1 related proteins in MK4MDD (count: 0)
DTNBP1 related GO terms (count: 33)
DTNBP1 related KEGG pathways (count: 0)
DTNBP1 related BioCarta pathways (count: 0)
DTNBP1 related Reactome pathways (count: 3)
DTNBP1 related interactors from protein-protein interaction data in HPRD (count: 10)