MK4MDD

Gene Report

Basic Information
Approved Symbol CACNA1C
Approved Name calcium channel, voltage-dependent, L type, alpha 1C subunit
Previous Symbol CCHL1A1, CACNL1A1
Symbol Alias Cav1.2, CACH2, CACN2, TS, LQT8
Location 12p13.3
Position chr12:2800366-2807114 (+)
External Links Entrez Gene: 775
Ensembl: ENSG00000151067
UCSC: uc001qjy.3
HGNC ID: 1390
No. of Studies (Positive/Negative) 2(1/1) Help
Type Literature-origin

Positive relationships between CACNA1C and MDD (count: 0)
Positive relationships between CACNA1C and other components at different levels (count: 7) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of CACNA1C in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between CACNA1C and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
CACNA1C Frazier, 2014 Patients and nomal controls ANK3, CACNA1C, and DGKH genotype groups were not associated ...... ANK3, CACNA1C, and DGKH genotype groups were not associated with the presence of mood disorder More...

Negative relationships between CACNA1C and other components at different levels (count: 0) Help
CACNA1C related SNPs in MK4MDD (count: 0)
CACNA1C related proteins in MK4MDD (count: 0)
CACNA1C related GO terms (count: 39)
CACNA1C related KEGG pathways (count: 11)
CACNA1C related BioCarta pathways (count: 0)
CACNA1C related Reactome pathways (count: 9)
CACNA1C related interactors from protein-protein interaction data in HPRD (count: 8)