SNP Report

Name	rs1006737 dbSNP Ensembl
Location	Chrchr12:2345295(Forward)
Variant Alleles	G/A
Ancestral Allele	G
Annotation	intron_variant
Consequence to Transcript	intron_variant(ENST00000327702, ENST00000335762, ENST00000344100, ENST00000347598, ENST00000399591, ENST00000399595, ENST00000399597, ENST00000399601, ENST00000399603, ENST00000399606, ENST00000399617, ENST00000399621, ENST00000399629, ENST00000399634, ENST00000399637, ENST00000399638, ENST00000399641, ENST00000399644, ENST00000399649, ENST00000399655, ENST00000402845, ENST00000406454, ENST00000480911, LRG_334_t1, LRG_334_t2, LRG_334_t3, LRG_334_t4)
No. of Studies (Positive/Negative)	2 (2/0)

Reference	Research Type	Statistical Result	Relation Description
Green, 2010	patients and normal controls	P-value=0.013	We found that the risk allele conferred increased risk for s...... We found that the risk allele conferred increased risk for schizophrenia (P=0.034) and recurrent major depression (P=0.013) with similar effect sizes to those previously observed in BD (allelic odds ratio approximately 1.15). More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
rs1006737		Depressed mood(depression severity)	symptoms	Casamassima, 2010	patients and normal controls	P-value = 0.04; beta = -0.4	The rs1006737 risk allele was significantly associated with ...... The rs1006737 risk allele was significantly associated with lesser baseline depression severity (P = 0.04; beta = -0.4) and decreased likelihood of insomnia (P = 0.047; beta = -0.22) More...

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Note:
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Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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3. The network is generated using Cytoscape Web

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	Literature-origin; SNP mapped	1(1/0)