MK4MDD

Gene Report

Basic Information
Approved Symbol NKX2-2
Approved Name NK2 homeobox 2
Previous Symbol NKX2B
Previous Name "NK-2 (Drosophila) homolog B", "NK2 transcription factor related, locus 2 (Drosophila)"
Symbol Alias NKX2.2
Location 20p11.22
Position chr20:21494308-21494664 (-)
External Links Entrez Gene: 4821
Ensembl: ENSG00000125820
UCSC: uc002wsi.3
HGNC ID: 7835
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between NKX2-2 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
NKX2B Aston, 2005 patients and normal controls Genes altered in major depressive disorder Genes altered in major depressive disorder

Positive relationships between NKX2-2 and other components at different levels (count: 0) Help
Positive relationship network of NKX2-2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between NKX2-2 and MDD (count: 0)
Negative relationships between NKX2-2 and other components at different levels (count: 0) Help
NKX2-2 related SNPs in MK4MDD (count: 0)
NKX2-2 related proteins in MK4MDD (count: 0)
NKX2-2 related GO terms (count: 30)
NKX2-2 related KEGG pathways (count: 1)
NKX2-2 related BioCarta pathways (count: 0)
NKX2-2 related Reactome pathways (count: 4)
NKX2-2 related interactors from protein-protein interaction data in HPRD (count: 1)