MK4MDD

Gene Report

Basic Information
Approved Symbol WFS1
Approved Name Wolfram syndrome 1 (wolframin)
Previous Symbol DFNA6, DFNA14, DFNA38
Symbol Alias DIDMOAD, WFS
Location 4p16.1
Position chr4:6304196-6304992 (+)
External Links Entrez Gene: 7466
Ensembl: ENSG00000109501
UCSC: uc003gix.3
HGNC ID: 12762
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin; SNP mapped

Positive relationships between WFS1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
WFS1 Koido, 2005 patients and normal controls Five SNPs in the WFS1 gene were associated with major depres...... Five SNPs in the WFS1 gene were associated with major depressive disorder More...

Positive relationships between WFS1 and other components at different levels (count: 0) Help
Positive relationship network of WFS1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between WFS1 and MDD (count: 0)
Negative relationships between WFS1 and other components at different levels (count: 0) Help
WFS1 related SNPs in MK4MDD (count: 1)
WFS1 related proteins in MK4MDD (count: 0)
WFS1 related GO terms (count: 37)
WFS1 related KEGG pathways (count: 0)
WFS1 related BioCarta pathways (count: 0)
WFS1 related Reactome pathways (count: 0)
WFS1 related interactors from protein-protein interaction data in HPRD (count: 1)