MK4MDD

Gene Report

Basic Information
Approved Symbol ARL4C
Approved Name ADP-ribosylation factor-like 4C
Previous Symbol ARL7
Previous Name "ADP-ribosylation factor-like 7"
Symbol Alias LAK
Location 2q37.2
Position chr2:235405231-235405693 (-)
External Links Entrez Gene: 10123
Ensembl: ENSG00000188042
UCSC: uc002vvn.3
HGNC ID: 698
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between ARL4C and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
ARL7 Sequeira A, 2009 patients and nomal controls Group: P-value=0.001, F=10.5; Substance: P-value=0.009, F=8.9 Genes differentially expressed after an ANCOVA analysis betw...... Genes differentially expressed after an ANCOVA analysis between the three groups(C = control, S = suicide, SMD = suicide with major depression). More...
ARL4C Jansen R, 2015 patients and normal controls P-value(MDD Affymetrix U219)=0.00011;P-value(MDD RNA-seq)=0.021;P-value(MDD meta)=1.4E-05;FDR (MDD meta)=0.065; "Mostafavi et al studied gene expression differences between...... "Mostafavi et al studied gene expression differences between 463 MDD cases and 459 controls using RNA-seq measurements. The P-values and directions of effects from this study were compared and meta-analyzed with our findings.When meta analyzing the P-values from the two studies, (weighted Z-score method), 12 genes were differentially expressed at FDRo0.1 (CALM1, FCRL6, APOBEC3G, SRSF5, RAP2B, PIPOX, PRR5L, HAGHL, ARL4C, NMUR1, KLRD1 and KCNJ2)" More...

Positive relationships between ARL4C and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of ARL4C in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between ARL4C and MDD (count: 0)
Negative relationships between ARL4C and other components at different levels (count: 0) Help
ARL4C related SNPs in MK4MDD (count: 0)
ARL4C related proteins in MK4MDD (count: 0)
ARL4C related GO terms (count: 11)
ARL4C related KEGG pathways (count: 0)
ARL4C related BioCarta pathways (count: 0)
ARL4C related Reactome pathways (count: 0)
ARL4C related interactors from protein-protein interaction data in HPRD (count: 1)