MK4MDD

Gene Report

Basic Information
Approved Symbol SIRT1
Approved Name sirtuin 1
Previous Name "sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1", "sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)"
Symbol Alias SIR2L1
Location 10q21
Position chr10:69676351-69678147 (+)
External Links Entrez Gene: 23411
Ensembl: ENSG00000096717
UCSC: uc001jnd.3
HGNC ID: 14929
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between SIRT1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
SIRT1 Kishi, 2010 patients and normal controls We found an association between rs10997875 in SIRT1 gene and...... We found an association between rs10997875 in SIRT1 gene and MDD in the allele/genotype analysis. More...

Positive relationships between SIRT1 and other components at different levels (count: 0) Help
Positive relationship network of SIRT1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between SIRT1 and MDD (count: 0)
Negative relationships between SIRT1 and other components at different levels (count: 0) Help
SIRT1 related SNPs in MK4MDD (count: 0)
SIRT1 related proteins in MK4MDD (count: 0)
SIRT1 related GO terms (count: 151)
SIRT1 related KEGG pathways (count: 0)
SIRT1 related BioCarta pathways (count: 1)
SIRT1 related Reactome pathways (count: 0)
SIRT1 related interactors from protein-protein interaction data in HPRD (count: 14)