Gene Report

Basic Information

Approved Symbol	MFRP
Approved Name	membrane frizzled-related protein
Symbol Alias	FLJ30570, rd6, NNO2, C1QTNF5
Name Alias	membrane-type frizzled-related protein, "complement C1q tumor necrosis factor-related protein 5 precursor variant 1"
Location	11q23.3
Position	chr11:119209652-119217383 (-)
External Links	Entrez Gene: 83552 Ensembl: ENSG00000235718 HGNC ID: 18121
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between MFRP and MDD (count: 0)

Positive relationships between MFRP and other components at different levels (count: 1)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name (Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
Name in Literature	Related Components
MFRP		Depression-like behaviors from animal model(depressive-like behavior)	cognition and behavior	Andrus, 2010	animal model		Differentially expressed depression genes hippocampus, (fold...... Differentially expressed depression genes hippocampus, (fold change > 2). More...

Positive relationship network of MFRP in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between MFRP and MDD (count: 0)

Negative relationships between MFRP and other components at different levels (count: 0)

MFRP related SNPs in MK4MDD (count: 0)

MFRP related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Membrane frizzled-related protein	Q9BY79	0(0/0)	Gene mapped

MFRP related GO terms (count: 3)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0009790	embryo development	biological process	NAS[11263980]
GO:0003674	molecular_function	molecular function	ND
GO:0016021	integral to membrane	cellular component	TAS[11263980]

MFRP related KEGG pathways (count: 0)

MFRP related BioCarta pathways (count: 0)

MFRP related Reactome pathways (count: 0)

MFRP related interactors from protein-protein interaction data in HPRD (count: 1)

Gene Report

Gene mapped GO terms