MK4MDD

Gene Report

Basic Information
Approved Symbol HDAC5
Approved Name histone deacetylase 5
Symbol Alias KIAA0600, NY-CO-9, FLJ90614
Location 17q21
Position chr17:42200872-42201009 (-)
External Links Entrez Gene: 10014
Ensembl: ENSG00000108840
UCSC: uc002iff.1
HGNC ID: 14068
No. of Studies (Positive/Negative) 3(3/0) Help
Type Literature-origin

Positive relationships between HDAC5 and MDD (count: 3)
Name in Literature Reference Research Type Statistical Result Relation Description Help
HDAC5 Iga, 2007 patients and normal controls Levels of HDAC5 and CREB mRNA were significantly higher in d...... Levels of HDAC5 and CREB mRNA were significantly higher in drug-free depressive patients than those of controls More...
histone deacetylase 5 Hobara, 2010 patients and normal controls In MDD, the expression of HDAC2 and -5 mRNA was increased in...... In MDD, the expression of HDAC2 and -5 mRNA was increased in a depressive state, but not in a remissive state, compared to controls. More...
HDAC5 Belzeaux, 2010 patients and normal controls We also observed that variations in other mRNA expression we...... We also observed that variations in other mRNA expression were associated with treatment efficacy or clinical improvement (CREB1, HDAC5, HSPA2, HTR1B, HTR2A, and SLC6A4/5HTT). More...

Positive relationships between HDAC5 and other components at different levels (count: 0) Help
Positive relationship network of HDAC5 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between HDAC5 and MDD (count: 0)
Negative relationships between HDAC5 and other components at different levels (count: 0) Help
HDAC5 related SNPs in MK4MDD (count: 0)
HDAC5 related proteins in MK4MDD (count: 0)
HDAC5 related GO terms (count: 54)
HDAC5 related KEGG pathways (count: 0)
HDAC5 related BioCarta pathways (count: 4)
HDAC5 related Reactome pathways (count: 0)
HDAC5 related interactors from protein-protein interaction data in HPRD (count: 37)