MK4MDD

Gene Report

Basic Information
Approved Symbol IL12A
Approved Name interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
Previous Symbol NKSF1
Symbol Alias CLMF, IL-12A, p35, NFSK
Name Alias "natural killer cell stimulatory factor 1, 35 kD subunit", "cytotoxic lymphocyte maturation factor 1, p35", "interleukin 12, p35", "IL-12, subunit p35", "NF cell stimulatory factor chain 1", "interleukin-12 alpha chain", "IL35 subunit"
Location 3q25.33
Position chr3:159713347-159713700 (+)
External Links Entrez Gene: 3592
Ensembl: ENSG00000168811
UCSC: uc003fcx.3
HGNC ID: 5969
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin; Protein mapped

Positive relationships between IL12A and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
IL-12A Shelton, 2011 patients and normal controls Gene set analysis suggested up-regulation of a variety of pr...... Gene set analysis suggested up-regulation of a variety of pro- and anti-inflammatory cytokines, including interleukin 1alpha (IL-1alpha), IL-2, IL-3, IL-5, IL-8, IL-9, IL-10, IL-12A, IL-13, IL-15, IL-18, interferon gamma (IFNgamma), and lymphotoxin alpha (TNF superfamily member 1). More...

Positive relationships between IL12A and other components at different levels (count: 0) Help
Positive relationship network of IL12A in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between IL12A and MDD (count: 0)
Negative relationships between IL12A and other components at different levels (count: 0) Help
IL12A related SNPs in MK4MDD (count: 0)
IL12A related proteins in MK4MDD (count: 1)
IL12A related GO terms (count: 38)
IL12A related KEGG pathways (count: 7)
IL12A related BioCarta pathways (count: 7)
IL12A related Reactome pathways (count: 0)
IL12A related interactors from protein-protein interaction data in HPRD (count: 6)