MK4MDD

Gene Report

Basic Information
Approved Symbol TNFRSF1B
Approved Name tumor necrosis factor receptor superfamily, member 1B
Previous Symbol TNFR2
Symbol Alias TNFBR, TNFR80, TNF-R75, TNF-R-II, p75, CD120b
Location 1p36.22
Position chr1:12267078-12269277 (+)
External Links Entrez Gene: 7133
Ensembl: ENSG00000028137
UCSC: uc001att.3
HGNC ID: 11917
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin; Protein mapped

Positive relationships between TNFRSF1B and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
TNFR2 Dean B, 2012 patients and normal controls levels of TNFR2 mRNA was decreased in BA 46 in people with m...... levels of TNFR2 mRNA was decreased in BA 46 in people with mood disorders (MDD=-51%; BD=-67%) More...

Positive relationships between TNFRSF1B and other components at different levels (count: 2) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of TNFRSF1B in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between TNFRSF1B and MDD (count: 0)
Negative relationships between TNFRSF1B and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


TNFRSF1B related SNPs in MK4MDD (count: 0)
TNFRSF1B related proteins in MK4MDD (count: 1)
TNFRSF1B related GO terms (count: 27)
TNFRSF1B related KEGG pathways (count: 3)
TNFRSF1B related BioCarta pathways (count: 8)
TNFRSF1B related Reactome pathways (count: 0)
TNFRSF1B related interactors from protein-protein interaction data in HPRD (count: 14)