MK4MDD

Gene Report

Basic Information
Approved Symbol MED12
Approved Name mediator complex subunit 12
Previous Symbol TNRC11, FGS1
Previous Name "trinucleotide repeat containing 11 (THR-associated protein, 230kDa subunit)", "mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae)", "FG syndrome 1"
Symbol Alias CAGH45, HOPA, OPA1, TRAP230, KIAA0192, OKS
Location Xq13
Position chrX:70362069-70362304 (+)
External Links Entrez Gene: 9968
Ensembl: ENSG00000184634
UCSC: uc004dyy.3
HGNC ID: 11957
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between MED12 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
HOPA Philibert, 2002 patients and normal controls HOPA polymorphisms were associated with an increased risk fo...... HOPA polymorphisms were associated with an increased risk for major depression. More...

Positive relationships between MED12 and other components at different levels (count: 0) Help
Positive relationship network of MED12 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between MED12 and MDD (count: 0)
Negative relationships between MED12 and other components at different levels (count: 0) Help
MED12 related SNPs in MK4MDD (count: 0)
MED12 related proteins in MK4MDD (count: 0)
MED12 related GO terms (count: 43)
MED12 related KEGG pathways (count: 0)
MED12 related BioCarta pathways (count: 0)
MED12 related Reactome pathways (count: 2)
MED12 related interactors from protein-protein interaction data in HPRD (count: 9)