MK4MDD

Gene Report

Basic Information
Approved Symbol DNMT3B
Approved Name DNA (cytosine-5-)-methyltransferase 3 beta
Location 20q11.2
Position chr20:31395710-31397162 (+)
External Links Entrez Gene: 1789
Ensembl: ENSG00000088305
UCSC: uc002wyc.3
HGNC ID: 2979
No. of Studies (Positive/Negative) 2(1/1) Help
Type Literature-origin

Positive relationships between DNMT3B and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
DNMT3B Higuchi, 2011 patients only We found that the levels of DNMT1 mRNA were significantly de...... We found that the levels of DNMT1 mRNA were significantly decreased in a depressive but not in a remissive state of MDD and BPD. In addition, the levels of DNMT3B mRNA in MDD were significantly increased in a depressive but not in a remissive state. More...

Positive relationships between DNMT3B and other components at different levels (count: 0) Help
Positive relationship network of DNMT3B in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between DNMT3B and MDD (count: 0)
Negative relationships between DNMT3B and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


DNMT3B related SNPs in MK4MDD (count: 0)
DNMT3B related proteins in MK4MDD (count: 0)
DNMT3B related GO terms (count: 44)
DNMT3B related KEGG pathways (count: 1)
DNMT3B related BioCarta pathways (count: 0)
DNMT3B related Reactome pathways (count: 0)
DNMT3B related interactors from protein-protein interaction data in HPRD (count: 16)