MK4MDD

Gene Report

Basic Information
Approved Symbol DNMT1
Approved Name DNA (cytosine-5-)-methyltransferase 1
Previous Symbol DNMT
Symbol Alias MCMT, CXXC9
Location 19p13.2
Position chr19:10305762-10305783 (-)
External Links Entrez Gene: 1786
Ensembl: ENSG00000130816
UCSC: uc010xlc.2
HGNC ID: 2976
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between DNMT1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
DNMT1 Higuchi, 2011 patients only We found that the levels of DNMT1 mRNA were significantly de...... We found that the levels of DNMT1 mRNA were significantly decreased in a depressive but not in a remissive state of MDD and BPD. In addition, the levels of DNMT3B mRNA in MDD were significantly increased in a depressive but not in a remissive state. More...

Positive relationships between DNMT1 and other components at different levels (count: 0) Help
Positive relationship network of DNMT1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between DNMT1 and MDD (count: 0)
Negative relationships between DNMT1 and other components at different levels (count: 0) Help
DNMT1 related SNPs in MK4MDD (count: 0)
DNMT1 related proteins in MK4MDD (count: 0)
DNMT1 related GO terms (count: 61)
DNMT1 related KEGG pathways (count: 1)
DNMT1 related BioCarta pathways (count: 0)
DNMT1 related Reactome pathways (count: 0)
DNMT1 related interactors from protein-protein interaction data in HPRD (count: 17)