MK4MDD

Gene Report

Basic Information
Approved Symbol APC
Approved Name adenomatous polyposis coli
Previous Name "adenomatosis polyposis coli"
Symbol Alias DP2, DP3, DP2.5, PPP1R46
Name Alias "protein phosphatase 1, regulatory subunit 46"
Location 5q21-q22
Position chr5:112179824-112181760 (+)
External Links Entrez Gene: 324
Ensembl: ENSG00000134982
UCSC: uc003kpy.4
HGNC ID: 583
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between APC and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
APC Aston, 2005 patients and normal controls Genes altered in major depressive disorder Genes altered in major depressive disorder

Positive relationships between APC and other components at different levels (count: 0) Help
Positive relationship network of APC in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between APC and MDD (count: 0)
Negative relationships between APC and other components at different levels (count: 0) Help
APC related SNPs in MK4MDD (count: 0)
APC related proteins in MK4MDD (count: 0)
APC related GO terms (count: 92)
APC related KEGG pathways (count: 6)
APC related BioCarta pathways (count: 6)
APC related Reactome pathways (count: 5)
APC related interactors from protein-protein interaction data in HPRD (count: 23)