
Gene Report
Approved Symbol | ABI1 |
---|---|
Approved Name | abl-interactor 1 |
Previous Symbol | SSH3BP1 |
Previous Name | spectrin SH3 domain binding protein 1 |
Symbol Alias | E3B1, ABI-1 |
Location | 10p12.1 |
Position | chr10:27035525-27150016 (-) |
External Links |
Entrez Gene: 10006 Ensembl: ENSG00000136754 UCSC: uc001isy.3 HGNC ID: 11320 |
No. of Studies (Positive/Negative) | 1(1/0)
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Type | Literature-origin |
Name in Literature | Reference | Research Type | Statistical Result | Relation Description | ![]() |
---|---|---|---|---|---|
abl-interactor 1 | Tochigi, 2008 | patients and normal controls | Genes differentially expressed in major depression Genes differentially expressed in major depression |
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus | Protein and Other Molecule | Cell and Molecular Pathway | Neural System | Cognition and Behavior | Symptoms and Signs | Environment | MDD |
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2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Approved Name | UniportKB | No. of Studies (Positive/Negative) | Source | |
---|---|---|---|---|
Abl interactor 1 | Q8IZP0 | 0(0/0) | Gene mapped |
Literature-origin GO terms | ||||
ID | Name | Type | Evidence | |
---|---|---|---|---|
GO:0005856 | cytoskeleton | cellular component | IEA | |
GO:0030054 | cell junction | cellular component | IEA |
Gene mapped GO terms | ||||
ID | Name | Type | Evidence | |
---|---|---|---|---|
GO:0030426 | growth cone | cellular component | IEA | |
GO:0008154 | actin polymerization or depolymerization | biological process | NAS[11516653] | |
GO:0008092 | cytoskeletal protein binding | molecular function | TAS[9593709] | |
GO:0030296 | protein tyrosine kinase activator activity | molecular function | IEA | |
GO:0005783 | endoplasmic reticulum | cellular component | TAS[9593709] | |
GO:0005515 | protein binding | molecular function | IPI | |
GO:0006928 | cellular component movement | biological process | IDA[11516653] | |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | biological process | TAS[9010225] | |
GO:0005829 | cytosol | cellular component | TAS[9010225] | |
GO:0008285 | negative regulation of cell proliferation | biological process | TAS[9010225] | |
GO:0005622 | intracellular | cellular component | IDA[17101133] | |
GO:0045202 | synapse | cellular component | IEA | |
GO:0018108 | peptidyl-tyrosine phosphorylation | biological process | IDA[17101133] | |
GO:0005634 | nucleus | cellular component | IEA | |
GO:0001756 | somitogenesis | biological process | IEA | |
GO:0030175 | filopodium | cellular component | IDA[11516653] | |
GO:0030027 | lamellipodium | cellular component | IDA[17101133] |

Gene | Interactor | Interactor in MK4MDD? | Experiment Type | PMID | |
---|---|---|---|---|---|
ABI1 | EVL | No | in vitro;in vivo | 16055720 | |
ABI1 | WASF2 | No | in vitro;in vivo | 15048123 , 16055720 , 17101133 | |
ABI1 | SOS2 | No | in vivo | 11003655 | |
ABI1 | ENAH | No | in vitro;in vivo;yeast 2-hybrid | 12672821 , 16055720 , 17101133 | |
ABI1 | SOS1 | No | in vitro;in vivo | 10499589 | |
ABI1 | VASP | No | in vitro;in vivo | 16055720 | |
ABI1 | ABL1 | No | in vitro;in vivo;yeast 2-hybrid | 8943360 , 9010225 , 12672821 , 11418237 , 9593709 , 17101133 | |
ABI1 | NCKAP1 | No | in vitro;yeast 2-hybrid | 15048123 , 11418237 , 16055720 | |
ABI1 | PAK2 | No | in vitro | 11956071 | |
ABI1 | NEB | No | in vitro | 15048123 | |
ABI1 | NCF1 | No | in vitro;yeast 2-hybrid | 12681507 | |
ABI1 | SPTAN1 | No | in vitro;yeast 2-hybrid | 9593709 | |
ABI1 | ABI1 | Yes | in vitro | 12672821 | |
ABI1 | EPS8 | Yes | in vitro;in vivo | 11099046 , 9010225 , 1049958 , 12127568 , 10499589 , 15289329 | |
ABI1 | HSPA8 | No | in vitro | 15048123 | |
ABI1 | SPTA1 | No | in vitro;in vivo;yeast 2-hybrid | 9593709 | |
ABI1 | MINK1 | No | yeast 2-hybrid | 15032605 | |
ABI1 | CYFIP2 | No | in vitro | 15048123 | |
ABI1 | NCK2 | No | in vitro | 11557983 | |
ABI1 | EPS8L1 | No | in vivo | 14565974 | |
ABI1 | NIN | No | in vitro | 15048123 | |
ABI1 | NCK1 | No | yeast 2-hybrid | 11418237 | |
ABI1 | WASF1 | No | in vitro | 15048123 |