MK4MDD

Gene Report

Basic Information
Approved Symbol KLRK1
Approved Name killer cell lectin-like receptor subfamily K, member 1
Previous Symbol D12S2489E
Previous Name "DNA segment on chromosome 12 (unique) 2489 expressed sequence"
Symbol Alias NKG2D, KLR, NKG2-D, CD314
Location 12p13.2-p12.3
Position chr12:10542542-10542653 (-)
External Links Entrez Gene: 22914
Ensembl: ENSG00000213809
UCSC: uc009zhj.3
HGNC ID: 18788
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between KLRK1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
KLRK1 Jansen R, 2015 patients and normal controls P-value=0.0000131;FDR=0.0363;beta=-0.265 P-values, FDR and betas of 18 genes differentially expressed...... P-values, FDR and betas of 18 genes differentially expressed between control and current MDD groups (FDR<0.05) More...

Positive relationships between KLRK1 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of KLRK1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between KLRK1 and MDD (count: 0)
Negative relationships between KLRK1 and other components at different levels (count: 0) Help
KLRK1 related SNPs in MK4MDD (count: 0)
KLRK1 related proteins in MK4MDD (count: 0)
KLRK1 related GO terms (count: 30)
KLRK1 related KEGG pathways (count: 1)
KLRK1 related BioCarta pathways (count: 0)
KLRK1 related Reactome pathways (count: 2)
KLRK1 related interactors from protein-protein interaction data in HPRD (count: 8)