MK4MDD

Gene Report

Basic Information
Approved Symbol ACSL4
Approved Name acyl-CoA synthetase long-chain family member 4
Previous Symbol FACL4, MRX63, MRX68
Previous Name "fatty-acid-Coenzyme A ligase, long-chain 4", "mental retardation, X-linked 63", "mental retardation, X-linked 68"
Symbol Alias ACS4, LACS4
Name Alias "lignoceroyl-CoA synthase", " long-chain fatty-acid-Coenzyme A ligase 4"
Location Xq22.3-q23
Position chrX:108976368-108976514 (-)
External Links Entrez Gene: 2182
Ensembl: ENSG00000068366
UCSC: uc004eoi.2
HGNC ID: 3571
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between ACSL4 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
FACL4 Covault J, 2004 Patients and nomal controls P = 0.003 We observed a significant excess of the T allele in subjects...... We observed a significant excess of the T allele in subjects with major depression, as compared with controls (49% vs. 38%; P = 0.003) More...

Positive relationships between ACSL4 and other components at different levels (count: 0) Help
Positive relationship network of ACSL4 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between ACSL4 and MDD (count: 0)
Negative relationships between ACSL4 and other components at different levels (count: 0) Help
ACSL4 related SNPs in MK4MDD (count: 0)
ACSL4 related proteins in MK4MDD (count: 0)
ACSL4 related GO terms (count: 29)
ACSL4 related KEGG pathways (count: 4)
ACSL4 related BioCarta pathways (count: 0)
ACSL4 related Reactome pathways (count: 0)
ACSL4 related interactors from protein-protein interaction data in HPRD (count: 0)