MK4MDD

Gene Report

Basic Information
Approved Symbol MAPK8
Approved Name mitogen-activated protein kinase 8
Previous Symbol PRKM8
Symbol Alias JNK, JNK1, SAPK1
Name Alias "JUN N-terminal kinase"
Location 10q11
Position chr10:49643073-49647395 (+)
External Links Entrez Gene: 5599
Ensembl: ENSG00000107643
UCSC: uc001jgp.3
HGNC ID: 6881
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between MAPK8 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
MAPK8 Aston, 2005 patients and normal controls Genes altered in major depressive disorder Genes altered in major depressive disorder

Positive relationships between MAPK8 and other components at different levels (count: 0) Help
Positive relationship network of MAPK8 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between MAPK8 and MDD (count: 0)
Negative relationships between MAPK8 and other components at different levels (count: 0) Help
MAPK8 related SNPs in MK4MDD (count: 0)
MAPK8 related proteins in MK4MDD (count: 0)
MAPK8 related GO terms (count: 69)
MAPK8 related KEGG pathways (count: 18)
MAPK8 related BioCarta pathways (count: 36)
MAPK8 related Reactome pathways (count: 17)
MAPK8 related interactors from protein-protein interaction data in HPRD (count: 70)