MK4MDD

Gene Report

Basic Information
Approved Symbol S100B
Approved Name S100 calcium binding protein B
Previous Name "S100 calcium binding protein, beta (neural)"
Symbol Alias S100beta
Location 21q22.3
Position chr21:48024926-48025035 (-)
External Links Entrez Gene: 6285
Ensembl: ENSG00000160307
UCSC: uc002zju.1
HGNC ID: 10500
No. of Studies (Positive/Negative) 3(1/2) Help
Type Literature-origin; Protein mapped

Positive relationships between S100B and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
S100B Klempan, 2009 patients and normal controls Selected differentially expressed genes in BA44 to BA47 (ANO...... Selected differentially expressed genes in BA44 to BA47 (ANOVA and t-test P < 0.01, fold change 1.3t) More...

Positive relationships between S100B and other components at different levels (count: 0) Help
Positive relationship network of S100B in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between S100B and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description
S100B Yang K, 2008 Patients and nomal controls There were no significant differences in the genotype distri...... There were no significant differences in the genotype distribution and allele frequencies between major depressive patients and healthy individuals More...
S100B Yang K, 2009 Patients and nomal controls Two single nucleotide polymorphisms did not display signific...... Two single nucleotide polymorphisms did not display significant associations with MDD. More...

Negative relationships between S100B and other components at different levels (count: 0) Help
S100B related SNPs in MK4MDD (count: 0)
S100B related proteins in MK4MDD (count: 1)
S100B related GO terms (count: 34)
S100B related KEGG pathways (count: 0)
S100B related BioCarta pathways (count: 0)
S100B related Reactome pathways (count: 0)
S100B related interactors from protein-protein interaction data in HPRD (count: 20)