Gene Report

Basic Information

Approved Symbol	ARPP19
Approved Name	cAMP-regulated phosphoprotein, 19kDa
Symbol Alias	ARPP-19, ARPP-16, ARPP16, ENSAL
Name Alias	"endosulfine alpha-like"
Location	15q11.2
Position	chr15:52861313-52861351 (-)
External Links	Entrez Gene: 10776 Ensembl: ENSG00000128989 UCSC: uc002acd.1 HGNC ID: 16967
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between ARPP19 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
ARPP-19	Sequeira, 2007	patients and normal controls		Selected differentially expressed genes in BA29 Selected differentially expressed genes in BA29

Positive relationships between ARPP19 and other components at different levels (count: 1)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name (Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
Name in Literature	Related Components
ARPP-19		Brodmann area 29(BA 29)	brain morphology and function	Sequeira, 2007	patients and normal controls		Selected differentially expressed genes in BA29 Selected differentially expressed genes in BA29

Positive relationship network of ARPP19 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between ARPP19 and MDD (count: 0)

Negative relationships between ARPP19 and other components at different levels (count: 0)

ARPP19 related SNPs in MK4MDD (count: 0)

ARPP19 related proteins in MK4MDD (count: 0)

ARPP19 related GO terms (count: 16)

ID	Name	Type	Evidence
Literature-origin GO terms
GO:0008601	protein phosphatase type 2A regulator activity	molecular function	ISS

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0015459	potassium channel regulator activity	molecular function	IDA[9653196]
GO:0005737	cytoplasm	cellular component	IEA
GO:0000278	mitotic cell cycle	biological process	TAS
GO:0034047	regulation of protein phosphatase type 2A activity	biological process	ISS
GO:0051301	cell division	biological process	IEA
GO:0005654	nucleoplasm	cellular component	TAS
GO:0045722	positive regulation of gluconeogenesis	biological process	IDA[9653196]
GO:0051721	protein phosphatase 2A binding	molecular function	ISS
GO:0007067	mitotic nuclear division	biological process	IMP[21164014]
GO:0004864	protein phosphatase inhibitor activity	molecular function	IEA
GO:0046326	positive regulation of glucose import	biological process	NAS[9653196]
GO:0000086	G2/M transition of mitotic cell cycle	biological process	IMP[21164014]
GO:0019212	phosphatase inhibitor activity	molecular function	ISS
GO:0043086	negative regulation of catalytic activity	biological process	IEA; ISS
GO:0005102	receptor binding	molecular function	IDA[9653196]

ARPP19 related KEGG pathways (count: 0)

ARPP19 related BioCarta pathways (count: 0)

ARPP19 related Reactome pathways (count: 0)

ARPP19 related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Literature-origin GO terms

Gene mapped GO terms