MK4MDD

Gene Report

Basic Information
Approved Symbol MSH2
Approved Name mutS homolog 2
Previous Symbol COCA1
Previous Name "mutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)", "mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)"
Symbol Alias HNPCC, HNPCC1
Location 2p21
Position chr2:47739574-47739716 (+)
External Links Entrez Gene: 4436
Ensembl: ENSG00000095002
UCSC: uc002rvy.2
HGNC ID: 7325
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between MSH2 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
mutS homolog 2 Tochigi, 2008 patients and normal controls Genes differentially expressed in major depression Genes differentially expressed in major depression

Positive relationships between MSH2 and other components at different levels (count: 0) Help
Positive relationship network of MSH2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between MSH2 and MDD (count: 0)
Negative relationships between MSH2 and other components at different levels (count: 0) Help
MSH2 related SNPs in MK4MDD (count: 0)
MSH2 related proteins in MK4MDD (count: 0)
MSH2 related GO terms (count: 65)
MSH2 related KEGG pathways (count: 3)
MSH2 related BioCarta pathways (count: 0)
MSH2 related Reactome pathways (count: 0)
MSH2 related interactors from protein-protein interaction data in HPRD (count: 11)