MK4MDD

Gene Report

Basic Information
Approved Symbol MBP
Approved Name myelin basic protein
Location 18q23
Position chr18:74844536-74844774 (-)
External Links Entrez Gene: 4155
Ensembl: ENSG00000197971
UCSC: uc010xfd.2
HGNC ID: 6925
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin; Protein mapped

Positive relationships between MBP and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
MBP Guilloux JP, 2012 patients and normal controls genes significantly affected in female MDD subjects genes significantly affected in female MDD subjects
MBP Sibille E, 2009 animal model; patients and nomal controls R=0.88, P-value<5E-6; y slope=1.14 Downregulated in MDD patients Downregulated in MDD patients

Positive relationships between MBP and other components at different levels (count: 0) Help
Positive relationship network of MBP in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between MBP and MDD (count: 0)
Negative relationships between MBP and other components at different levels (count: 0) Help
MBP related SNPs in MK4MDD (count: 0)
MBP related proteins in MK4MDD (count: 1)
MBP related GO terms (count: 23)
MBP related KEGG pathways (count: 0)
MBP related BioCarta pathways (count: 0)
MBP related Reactome pathways (count: 0)
MBP related interactors from protein-protein interaction data in HPRD (count: 43)