MK4MDD

Gene Report

Basic Information
Approved Symbol NGFR
Approved Name nerve growth factor receptor
Previous Name "nerve growth factor receptor (TNFR superfamily, member 16)"
Symbol Alias TNFRSF16, CD271, p75NTR
Name Alias "low affinity nerve growth factor receptor", "TNFR superfamily, member 16"
Location 17q21-q22
Position chr17:47590372-47592382 (+)
External Links Entrez Gene: 4804
Ensembl: ENSG00000064300
UCSC: uc002ioz.4
HGNC ID: 7809
No. of Studies (Positive/Negative) 2(0/2) Help
Type Literature-origin; SNP mapped; Protein mapped

Positive relationships between NGFR and MDD (count: 0)
Positive relationships between NGFR and other components at different levels (count: 0) Help
Positive relationship network of NGFR in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between NGFR and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
p75NTR Kunugi H, 2004 Patients and nomal controls P < 0.05, odds ratio 0.54, 95% CI 0.31-0.94 The minor allele (L205) was significantly decreased in the p...... The minor allele (L205) was significantly decreased in the patients than in the controls (P < 0.05, odds ratio 0.54, 95% CI 0.31-0.94), suggesting that this allele may have a protective effect against the development of major depression. More...

Negative relationships between NGFR and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


NGFR related SNPs in MK4MDD (count: 1)
NGFR related proteins in MK4MDD (count: 1)
NGFR related GO terms (count: 75)
NGFR related KEGG pathways (count: 2)
NGFR related BioCarta pathways (count: 3)
NGFR related Reactome pathways (count: 9)
NGFR related interactors from protein-protein interaction data in HPRD (count: 32)