MK4MDD

Gene Report

Basic Information
Approved Symbol IL3
Approved Name interleukin 3 (colony-stimulating factor, multiple)
Symbol Alias IL-3, MULTI-CSF, MCGF, MGC79398, MGC79399
Name Alias "multilineage-colony-stimulating factor", "hematopoietic growth factor", "P-cell stimulating factor", "mast-cell growth factor"
Location 5q23-q31
Position chr5:131398485-131398896 (+)
External Links Entrez Gene: 3562
Ensembl: ENSG00000164399
UCSC: uc003kwe.1
HGNC ID: 6011
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between IL3 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
IL-3 Shelton, 2011 patients and normal controls Gene set analysis suggested up-regulation of a variety of pr...... Gene set analysis suggested up-regulation of a variety of pro- and anti-inflammatory cytokines, including interleukin 1alpha (IL-1alpha), IL-2, IL-3, IL-5, IL-8, IL-9, IL-10, IL-12A, IL-13, IL-15, IL-18, interferon gamma (IFNgamma), and lymphotoxin alpha (TNF superfamily member 1). More...

Positive relationships between IL3 and other components at different levels (count: 0) Help
Positive relationship network of IL3 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between IL3 and MDD (count: 0)
Negative relationships between IL3 and other components at different levels (count: 0) Help
IL3 related SNPs in MK4MDD (count: 0)
IL3 related proteins in MK4MDD (count: 0)
IL3 related GO terms (count: 28)
IL3 related KEGG pathways (count: 6)
IL3 related BioCarta pathways (count: 8)
IL3 related Reactome pathways (count: 0)
IL3 related interactors from protein-protein interaction data in HPRD (count: 6)