BioCarta Pathway Report
Basic Information
| ID |
IL3_PATHWAY
|
| Name |
il3 pathway
|
| Brief Description |
IL 3 signaling pathway
|
| Full Description |
Interleukin-3 promotes the proliferation and differentiation of hematopoietic cells through binding to its receptor. The receptor for IL-3 is a heterodimer with a ligand-specific alpha chain (70 kD, CD123) and a common beta chain (shared with IL-5 and GM-CSF). Signaling is believed to be primarily through Stat5 and the MAPK pathways. |
IL3_PATHWAY related genes in MK4MDD (count: 5)
| Approved Symbol |
Approved Name |
Type |
No. of Studies (Positive/Negative) |
| CSF2RB |
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
Literature-origin
|
1(1/0) |
| PTPN6 |
protein tyrosine phosphatase, non-receptor type 6 |
Literature-origin
|
1(1/0) |
| IL3 |
interleukin 3 (colony-stimulating factor, multiple) |
Literature-origin
|
1(1/0) |
| HRAS |
v-Ha-ras Harvey rat sarcoma viral oncogene homolog |
Protein mapped
|
0(0/0) |
| FOS |
FBJ murine osteosarcoma viral oncogene homolog |
Literature-origin; Protein mapped
|
1(1/0) |
