MK4MDD

Gene Report

Basic Information
Approved Symbol NPAS2
Approved Name neuronal PAS domain protein 2
Symbol Alias MOP4, PASD4, bHLHe9
Location 2q11.2
Position chr2:101612413-101613289 (+)
External Links Entrez Gene: 4862
Ensembl: ENSG00000170485
UCSC: uc002tap.1
HGNC ID: 7895
No. of Studies (Positive/Negative) 2(1/1) Help
Type Literature-origin

Positive relationships between NPAS2 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
NPAS2 Soria, 2010 patients and normal controls In the MDD subsample, the same SNPs in CRY1 and NPAS2 of the...... In the MDD subsample, the same SNPs in CRY1 and NPAS2 of the combined sample remained associated More...

Positive relationships between NPAS2 and other components at different levels (count: 0) Help
Positive relationship network of NPAS2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between NPAS2 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
NPAS2 Byrne EM, 2014 Patients and nomal controls P-Values=0.39 These results show that while there are several circadian ge...... These results show that while there are several circadian genes that harbor SNPs with nominally significant P-values, there are no associations beyond what would be expected after controlling for the number of SNPs in each gene. The gene-based test not only controls for the number of SNPs, but also combines evidence from multiple SNPs after controlling for the linkage disequilibrium between them More...

Negative relationships between NPAS2 and other components at different levels (count: 0) Help
NPAS2 related SNPs in MK4MDD (count: 0)
NPAS2 related proteins in MK4MDD (count: 0)
NPAS2 related GO terms (count: 26)
NPAS2 related KEGG pathways (count: 1)
NPAS2 related BioCarta pathways (count: 0)
NPAS2 related Reactome pathways (count: 0)
NPAS2 related interactors from protein-protein interaction data in HPRD (count: 8)