MK4MDD

Gene Report

Basic Information
Approved Symbol RAPGEF6
Approved Name Rap guanine nucleotide exchange factor (GEF) 6
Previous Symbol PDZGEF2
Previous Name "PDZ domain containing guanine nucleotide exchange factor (GEF) 2"
Symbol Alias RA-GEF-2, PDZ-GEF2
Location 5q31.1
Position chr5:130970724-130970921 (-)
External Links Entrez Gene: 51735
Ensembl: ENSG00000158987
UCSC: uc010jdi.2
HGNC ID: 20655
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between RAPGEF6 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
RAPGEF6 Chu TT, 2009 Patients and nomal controls Down regulation, fold change([MD] vs [C]) 2.022933 Down regulation, fold change([MD] vs [C]) 2.022933

Positive relationships between RAPGEF6 and other components at different levels (count: 0) Help
Positive relationship network of RAPGEF6 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between RAPGEF6 and MDD (count: 0)
Negative relationships between RAPGEF6 and other components at different levels (count: 0) Help
RAPGEF6 related SNPs in MK4MDD (count: 0)
RAPGEF6 related proteins in MK4MDD (count: 0)
RAPGEF6 related GO terms (count: 15)
RAPGEF6 related KEGG pathways (count: 0)
RAPGEF6 related BioCarta pathways (count: 0)
RAPGEF6 related Reactome pathways (count: 0)
RAPGEF6 related interactors from protein-protein interaction data in HPRD (count: 6)