MK4MDD

Gene Report

Basic Information
Approved Symbol AANAT
Approved Name aralkylamine N-acetyltransferase
Previous Name "arylalkylamine N-acetyltransferase"
Symbol Alias SNAT
Name Alias "serotonin N-acetyltransferase"
Location 17q25.1
Position chr17:74466053-74466199 (+)
External Links Entrez Gene: 15
Ensembl: ENSG00000129673
UCSC: uc002jro.3
HGNC ID: 19
No. of Studies (Positive/Negative) 2(1/1) Help
Type Literature-origin

Positive relationships between AANAT and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
AANAT Soria, 2010 patients and normal controls P-value<0.01 Common variants (MAF > 2%) were included in a case-control a...... Common variants (MAF > 2%) were included in a case-control association analysis that showed significant association after multiple testing correction of two SNPs located in the promoter region of AANAT with MD: rs3760138 (P = 0.00006) and rs4238989 (P = 0.005) More...

Positive relationships between AANAT and other components at different levels (count: 0) Help
Positive relationship network of AANAT in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between AANAT and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
AANAT Byrne EM, 2014 Patients and nomal controls P-Values=0.24 These results show that while there are several circadian ge...... These results show that while there are several circadian genes that harbor SNPs with nominally significant P-values, there are no associations beyond what would be expected after controlling for the number of SNPs in each gene. The gene-based test not only controls for the number of SNPs, but also combines evidence from multiple SNPs after controlling for the linkage disequilibrium between them More...

Negative relationships between AANAT and other components at different levels (count: 0) Help
AANAT related SNPs in MK4MDD (count: 0)
AANAT related proteins in MK4MDD (count: 0)
AANAT related GO terms (count: 21)
AANAT related KEGG pathways (count: 1)
AANAT related BioCarta pathways (count: 0)
AANAT related Reactome pathways (count: 2)
AANAT related interactors from protein-protein interaction data in HPRD (count: 3)