Pathway Report

Name	postsynaptic membrane
GO Link	ID: GO:0045211 Name: postsynaptic membrane Type: cellular component
Description	cellular_component. A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology[ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
No. of Studies (Positive/Negative)	1 (1/0)

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
Postsynaptic membrane		SLC17A7(vesicular glutamate transporter 1 (VGLUT1))	gene	Tordera RM, 2011	animal model		genes invovled in this pathwy were regulated in frontal cort...... genes invovled in this pathwy were regulated in frontal cortex of VGLUT1(+/-) mice More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
GRM3	glutamate receptor, metabotropic 3	Literature-origin; SNP mapped; Protein mapped	3(3/0)
DISC1	disrupted in schizophrenia 1	Literature-origin; SNP mapped; Protein mapped	2(2/0)
KCTD12	potassium channel tetramerisation domain containing 12	Literature-origin	1(1/0)
TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	Literature-origin	1(1/0)
GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	Literature-origin	2(2/0)
CHRM2	cholinergic receptor, muscarinic 2	Literature-origin; SNP mapped; Protein mapped	2(1/1)
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	Literature-origin; Protein mapped	2(2/0)
GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1	Literature-origin; Protein mapped	1(1/0)
GABRA5	gamma-aminobutyric acid (GABA) A receptor, alpha 5	Literature-origin	1(1/0)
DLG2	discs, large homolog 2 (Drosophila)	Literature-origin	1(1/0)
GABRG1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	Literature-origin	1(1/0)
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	Literature-origin; Protein mapped	1(1/0)
DTNBP1	dystrobrevin binding protein 1	Literature-origin	2(1/1)
GRIK3	glutamate receptor, ionotropic, kainate 3	Literature-origin	1(1/0)
GRIA2	glutamate receptor, ionotropic, AMPA 2	Literature-origin	1(1/0)
GABRD	gamma-aminobutyric acid (GABA) A receptor, delta	Literature-origin	1(1/0)
GRID2	glutamate receptor, ionotropic, delta 2	Literature-origin	1(1/0)
GRIA1	glutamate receptor, ionotropic, AMPA 1	Literature-origin; Protein mapped	1(1/0)
SYNE1	spectrin repeat containing, nuclear envelope 1	Literature-origin	1(1/0)
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	Literature-origin	1(1/0)
CHRNA7	cholinergic receptor, nicotinic, alpha 7 (neuronal)	Literature-origin	1(1/0)
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	Literature-origin	1(1/0)
GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2	Literature-origin	2(2/0)
GABRB1	gamma-aminobutyric acid (GABA) A receptor, beta 1	Literature-origin	2(2/0)
DLG4	discs, large homolog 4 (Drosophila)	Literature-origin; Protein mapped	1(1/0)
NLGN1	neuroligin 1	Literature-origin	1(1/0)
PDLIM5	PDZ and LIM domain 5	Literature-origin; SNP mapped	1(1/0)
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	Literature-origin; Protein mapped	2(2/0)
GABRA2	gamma-aminobutyric acid (GABA) A receptor, alpha 2	Literature-origin	1(1/0)
GRIA3	glutamate receptor, ionotropic, AMPA 3	Literature-origin; Protein mapped	1(1/0)
GABRA3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	Literature-origin	2(2/0)
GABRR1	gamma-aminobutyric acid (GABA) A receptor, rho 1	Literature-origin	1(1/0)
GRIK5	glutamate receptor, ionotropic, kainate 5	Literature-origin	1(1/0)
GLRB	glycine receptor, beta	Literature-origin	1(1/0)
HTR3B	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	Literature-origin; SNP mapped	1(1/0)