MK4MDD

Pathway Report

Basic Information
Name postsynaptic membrane
GO Link ID: GO:0045211
Name: postsynaptic membrane
Type: cellular component
Description "cellular_component. A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane."" [ISBN:0198506732 ""Oxford Dictionary of Biochemistry and Molecular Biology[ISBN:0198506732 ""Oxford Dictionary of Biochemistry and Molecular Biology""]"
No. of Studies (Positive/Negative) 2 (2/0) Help

Positive relationship between postsynaptic membrane and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
postsynaptic membrane Network and C, 2015 patients only FDR q-value=0.09724434 The degree of rank correlation between pathways across pairs...... The degree of rank correlation between pathways across pairs of disorders was significant (Supplementary Tables 4 and 6), with 49 pathways with combined q-value <0.1 spanning the three adult disorders (Table 2, Supplementary Table 7). Of these, 16 are significant at q < 0.05, with the top pathway (GO:51568: histone H3-K4 methylation) having a q = 0.0003 (Table 2). These results are more significant than those observed in any of the disorders analyzed alone. We then use multidimensional scaling (MDS) to cluster these sets in terms of shared genes. More...

Positive relationships between postsynaptic membrane and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of postsynaptic membrane in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between postsynaptic membrane and MDD (count: 0)
Negative relationships between postsynaptic membrane and other components at different levels (count: 0) Help
Pathway postsynaptic membrane related genes in MK4MDD (count: 46)