Gene Report
Basic Information
| Approved Symbol | SYNE1 |
|---|---|
| Approved Name | spectrin repeat containing, nuclear envelope 1 |
| Previous Symbol | C6orf98 |
| Previous Name | chromosome 6 open reading frame 98 |
| Symbol Alias | SYNE-1B, KIAA0796, 8B, Nesprin-1, enaptin, MYNE1, CPG2, dJ45H2.2, SCAR8, ARCA1, Nesp1 |
| Name Alias | myocyte nuclear envelope protein 1, "nuclear envelope spectrin repeat-1" |
| Location | 6q24.2-q25.3 |
| Position | chr6:152442819-152958534 (-) |
| External Links |
Entrez Gene: 23345 Ensembl: ENSG00000131018 UCSC: uc003qou.4 HGNC ID: 17089 |
| No. of Studies (Positive/Negative) | 1(1/0)
|
| Type | Literature-origin |
Positive relationships between SYNE1 and MDD (count: 1)
| Name in Literature | Reference | Research Type | Statistical Result | Relation Description | |
|---|---|---|---|---|---|
| SYNE1 | Green EK, 2012 | patients and normal controls | P-value =0.032 | We have also examined the polymorphism in our recurrent unip...... We have also examined the polymorphism in our recurrent unipolar depression cases (n=1159) and control (n=2592) sample, and found that the risk allele was associated with risk for recurrent major depression (P=0.032, OR=1.118) More... |
Positive relationships between SYNE1 and other components at different levels (count: 0)
Positive relationship network of SYNE1 in MK4MDD
Network loading ...
Note:
1. The different color of the nodes denotes the level of the nodes.
| Genetic/Epigenetic Locus | Protein and Other Molecule | Cell and Molecular Pathway | Neural System | Cognition and Behavior | Symptoms and Signs | Environment | MDD |
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2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web
Negative relationships between SYNE1 and MDD (count: 0)
Negative relationships between SYNE1 and other components at different levels (count: 0)
SYNE1 related SNPs in MK4MDD (count: 0)
SYNE1 related proteins in MK4MDD (count: 1)
SYNE1 related GO terms (count: 22)
SYNE1 related KEGG pathways (count: 0)
SYNE1 related BioCarta pathways (count: 0)
SYNE1 related Reactome pathways (count: 0)
SYNE1 related interactors from protein-protein interaction data in HPRD (count: 7)