Gene Report

Basic Information

Approved Symbol	KCTD12
Approved Name	potassium channel tetramerisation domain containing 12
Previous Symbol	C13orf2
Previous Name	chromosome 13 open reading frame 2
Symbol Alias	KIAA1778, PFET1
Name Alias	predominantly fetal expressed T1 domain
Location	13q21
Position	chr13:77454304-77460540 (-)
External Links	Entrez Gene: 115207 Ensembl: ENSG00000178695 UCSC: uc010aeu.1 HGNC ID: 14678
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between KCTD12 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
KCTD12	Sibille E, 2009	animal model; patients and nomal controls	R=0.88, P-value<5E-6; y slope=1.08	Upregulated in MDD patients Upregulated in MDD patients

Positive relationships between KCTD12 and other components at different levels (count: 0)

Positive relationship network of KCTD12 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between KCTD12 and MDD (count: 0)

Negative relationships between KCTD12 and other components at different levels (count: 0)

KCTD12 related SNPs in MK4MDD (count: 0)

KCTD12 related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
BTB/POZ domain-containing protein KCTD12	Q96CX2	0(0/0)	Gene mapped

KCTD12 related GO terms (count: 7)

ID	Name	Type	Evidence
Literature-origin GO terms
GO:0045211	postsynaptic membrane	cellular component	IEA
GO:0030054	cell junction	cellular component	IEA

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0043235	receptor complex	cellular component	IEA
GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	biological process	IEA
GO:0051260	protein homooligomerization	biological process	IEA
GO:0042734	presynaptic membrane	cellular component	IEA
GO:0005886	plasma membrane	cellular component	IEA

KCTD12 related KEGG pathways (count: 0)

KCTD12 related BioCarta pathways (count: 0)

KCTD12 related Reactome pathways (count: 0)

KCTD12 related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Literature-origin GO terms

Gene mapped GO terms