MK4MDD

Symptoms Report

Basic Information
Name Increased agitation
Description "Psychomotor agitation is a series of unintentional and purposeless motions that stem from mental tension and anxiety of an individual. This includes pacing around a room, wringing one's hands, pulling off clothing and putting it back on and other similar actions. In more severe cases, the motions may become harmful to the individual, such as ripping, tearing or chewing at the skin around one's fingernails or lips to the point of bleeding. Psychomotor agitation is a symptom typically found in major depressive disorder or obsessive-compulsive disorder, and sometimes the manic phase in bipolar disorder, although it can also be a result of an excess intake of stimulants. The middle aged and the elderly are more at risk to express this condition."
No. of Studies (Positive/Negative) 35 (35/0) Help

Positive relationship between Increased agitation and MDD (count: 6)
Name in Literature Reference Research Type Statistical Result Relation Description Help
psychomotor activation Pasquini, 2004 patients only 0.90% The anger/irritability dimension was clinically relevant in ...... The anger/irritability dimension was clinically relevant in 23% of patients. Anger/aggressiveness was especially frequent (21.6%), whereas psychomotor activation was infrequent (0.9%). More...
agitation Olgiati, 2006 patients only Agitated depression (AD, a major depressive episode with psy...... Agitated depression (AD, a major depressive episode with psychomotor agitation) was present in 19% of the sample. More...
agitation Leventhal, 2008 patients only Results were suggestive that agitated depression was a relat...... Results were suggestive that agitated depression was a relatively specific phenotypic syndrome characterized by irritability, arousal, physical complaints, and vulnerability to anxiety disorders and alcohol dependence; low stability across depressive episodes; and low heritability. More...
increase in energy Yonkers, 2009 patients and normal controls Appetite increase, oversleeping and increase in energy (e.g....... Appetite increase, oversleeping and increase in energy (e.g., agitation) were uninformative with regard to an MDD diagnosis. More...
agitation Taylor, 2010 patients only P-value < .05 Decreased agitation, increased psychological anxiety, increa...... Decreased agitation, increased psychological anxiety, increased loss of appetite, increased loss of libido, and increased hypochondriasis were all risk factors for relapse and recurrence over a 2-year follow-up (all p<.05), after stratifying on number of previous episodes and controlling for age at onset and whether A-CT responders received continuation phase CT instead of assessment only control. More...
psychological anxiety Taylor, 2010 patients only P-value < .05 Decreased agitation, increased psychological anxiety, increa...... Decreased agitation, increased psychological anxiety, increased loss of appetite, increased loss of libido, and increased hypochondriasis were all risk factors for relapse and recurrence over a 2-year follow-up (all p<.05), after stratifying on number of previous episodes and controlling for age at onset and whether A-CT responders received continuation phase CT instead of assessment only control. More...

Positive relationships between Increased agitation and other components at different levels (count: 48) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Increased agitation in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Increased agitation and MDD (count: 0)
Negative relationships between Increased agitation and other components at different levels (count: 0) Help