The temporal lobe is a region of the cerebral cortex that is located beneath the Sylvian fissure on both cerebral hemispheres of the mammalian brain. The temporal lobe is involved in auditory perception and is home to the primary auditory cortex.
Brain Function
Temporal Lobe- associated with perception and recognition of auditory stimuli, memory, and speech
Both approaches indicated that the depressed sample had an a......
Both approaches indicated that the depressed sample had an abnormality in topographic distribution of blood flow, in addition to the global deficit. The scaled subprofile model identified the topographic abnormality as being due to flow reduction in the depressed patients in selective frontal, central, superior temporal, and anterior parietal regions.More...
A significant reduction in binding index (BI) of [(18)F]FESP......
A significant reduction in binding index (BI) of [(18)F]FESP ( P=0.003 ANOVA, P=0.001 ANCOVA) was found in DN(drug-naive) patients in the frontal, occipital, temporal and cingulate corticesMore...
Mean volume of T2-WIH was significantly greater (p=0.004) in......
Mean volume of T2-WIH was significantly greater (p=0.004) in depressed subjects. In the control group T2-WIH(T2-weighted image 'hyperintensities') were exclusively located in the supratentorial hemispheral white matter while in the depressed group T2-WIH were also found in basal ganglia, temporal lobe, cerebellum and brainstem.More...
For happy words, depressed subjects exhibited less activatio......
For happy words, depressed subjects exhibited less activation than did controls to happy words in fronto-temporal and limbic regions. For sad words, depressed subjects showed more activation than did controls in the inferior parietal lobule and less activation in the superior temporal gyrus and cerebellumMore...
Depressed borderline patients had greater relative activity ......
Depressed borderline patients had greater relative activity in parietotemporal cortical regions (BA 40, BA 22, and BA 42) before and after FEN (fenfluramine) activation compared to those without BPD (borderline personality disorder). Borderline pathology in the context of a Major Depressive Disorder is associated with altered activity in parietotemporal cortical regions.More...
The MDD participants had greater activation compared with th......
The MDD participants had greater activation compared with the control group in frontal and anterior temporal areas during correct rejections (inhibition). More...
Comorbid MDD was associated with a significantly more pronou......
Comorbid MDD was associated with a significantly more pronounced reduction in 5-HT(1A) receptor binding in TLE ( temporal lobe epilepsy) patients, extending into non-lesional limbic brain areas outside the epileptic focus.More...
Adolescents with depression compared to healthy controls dem......
Adolescents with depression compared to healthy controls demonstrated reduced activation in putamen, insula and temporal lobes during the Switch task.More...
Before treatment, excessive high-beta (18-30 Hz) activity wa......
Before treatment, excessive high-beta (18-30 Hz) activity was noted in several brain regions located in the fronto-temporal regions.More...
Local areas showing an increase of MD (mean diffusivity) in ......
Local areas showing an increase of MD (mean diffusivity) in depressive patients were observed in the temporal lobeMore...
In a between-group comparison, patients showed significantly......
In a between-group comparison, patients showed significantly reduced activation in the insula, temporal and occipital cortices. More...
Depressed patients were found to have smaller temporal lobes......
Depressed patients were found to have smaller temporal lobes bilaterally, medulla and right hippocampus at baseline.More...
The MDD patients exhibited reduced nodal centralities in the......
The MDD patients exhibited reduced nodal centralities in the temporal regions. More...
Our results showed that the topological properties of depres......
Our results showed that the topological properties of depressed adolescents' networks were significantly disrupted compared with HC. Dysregulation of brain regions were found in the temporal cortices. More...
Positive relationships between Temporal Lobe and other components at different levels (count: 5)
Genetic/epigenetic locus
Protein and other molecule
Cell and molecular pathway
Neural system
Cognition and behavior
Symptoms and signs
Environment
Positive relationship network of Temporal Lobe in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus
Protein and Other Molecule
Cell and Molecular Pathway
Neural System
Cognition and Behavior
Symptoms and Signs
Environment
MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node.
Right-click will show also the menus to link to the report page of the node and remove the node and related edges.
Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web
Negative relationships between Temporal Lobe and MDD (count: 0)
Negative relationships between Temporal Lobe and other components at different levels (count: 0)