|Name||Cell adhesion molecules|
Name: cell adhesion_molecules_cams
Brief Description: Cell adhesion molecules (CAMs)
Full Description: Cell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, embryogenesis, and development of neuronal tissue. There are four main groups: the integrin family, the immunoglobulin superfamily, selectins, and cadherins. Membrane proteins that mediate immune cellcell interactions fall into different categories, namely those involved in antigen recognition, costimulation and cellular adhesion. Furthermore cell-cell adhesions are important for brain morphology and highly coordinated brain functions such as memory and learning. During early development of the nervous system, neurons elongate their axons towards their targets and establish and maintain synapses through formation of cell-cell adhesions. Cell-cell adhesions also underpin axon-axon contacts and link neurons with supporting schwann cells and oligodendrocytes.
|No. of Studies (Positive/Negative)||2 (2/0)|
1. The different color of the nodes denotes the level of the nodes.
|Genetic/Epigenetic Locus||Protein and Other Molecule||Cell and Molecular Pathway||Neural System||Cognition and Behavior||Symptoms and Signs||Environment||MDD|
3. The network is generated using Cytoscape Web