MK4MDD

Protein Report

Basic Information
Protein Name Amine oxidase [flavin-containing] A
UniPortKB P21397
No. of Studies (Positive/Negative) 4 (4/0) Help
Type Literature-origin
Positive relationship between Amine oxidase [flavin-containing] A and MDD (count: 4)
Name in Literature Reference Research Type Statistical Result Relation Description Help
monoamine oxidase A (MAO-A) Meyer, 2006 patients and normal controls P-value<=0.001 The MAO-A DVS (specific distribution volume) was highly sign...... The MAO-A DVS (specific distribution volume) was highly significantly elevated in every brain region assessed (t test; P=.001 to 3x10(-7)). The MAO-A DVS was elevated on average by 34% (2 SDs) throughout the brain during major depression. More...
monoamine oxidase A (MAO-A) Meyer, 2009 patients and normal controls Monoamine oxidase A V(T), an index of MAO-A density, was sig...... Monoamine oxidase A V(T), an index of MAO-A density, was significantly elevated in each brain region both during MDE (major depressive episodes) and after SSRI treatment as compared with healthy controls. More...
monoamine oxidase A Zhang, 2010 patients and normal controls quantity of MAOA messenger RNA was significantly higher in p...... quantity of MAOA messenger RNA was significantly higher in patients with MDD than in control subjects (fold change = 5.28, p = 1.7 ¡Á 10-7) More...
MAO A Johnson, 2011 patients and normal controls P-value<0.05 An increase (approximately 40%; p<0.05) in MAO A protein lev...... An increase (approximately 40%; p<0.05) in MAO A protein levels within the MDD groups compared with controls, the MAO A catalytic activity was significantly greater in both MDD groups compared with controls More...

Positive relationships between Amine oxidase [flavin-containing] A and other components at different levels (count: 12) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment

Positive relationship network of Amine oxidase [flavin-containing] A in MK4MDD
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network_footer.jsp Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between Amine oxidase [flavin-containing] A and MDD (count: 0)
Negative relationships between Amine oxidase [flavin-containing] A and other components at different levels (count: 0) Help
Related Gene Info
Gene Symbol Gene Name Type No. of Studies (Positive/Negative) Add to Relationship Set
MAOA monoamine oxidase A Literature-origin; SNP mapped; Protein mapped 13 (9/4)