Brain Morphology and Function Report

Name	rostral anterior cingulate
Brain Morphology	Please reference to the description for Anterior cingulate cortex
No. of Studies (Positive/Negative)	12(12/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
rostral anterior cingulate gyrus (rACG)	Wagner, 2006	patients and normal controls		Comparison of patients with control subjects in the interfer...... Comparison of patients with control subjects in the interference condition revealed hyperactivity in rostral anterior cingulate gyrus (rACG) in depressive patients, which correlated strongly with the Stroop interference. More...
rostral anterior cingulate	Kumar, 2008	patients and normal controls		Patients with MDD had significantly reduced reward-learning ...... Patients with MDD had significantly reduced reward-learning signals in rostral and dorsal anterior cingulate. More...
rostral anterior cingulate gyrus	Saxena, 2003	patients only	z=2.91	improvement of major depressive disorder symptoms was signif...... improvement of major depressive disorder symptoms was significantly correlated with higher pretreatment (glucose) metabolism in the medial prefrontal cortex and rostral anterior cingulate gyrus (Talairach coordinates: x=0, y=62, z=10) (z=2.91). More...
rostral anterior cingulate	Rose, 2006	patients and normal controls	cluster size (K(E))/volume = 128/1024 mm3, corrected P-value = 0.025	Random effects analysis of the functional imaging data revea...... Random effects analysis of the functional imaging data revealed a significant difference in load-dependent activation in the rostral anterior cingulate between patients and controls. While both participant groups exhibited a significant decrease in activation in this region with increased task difficulty, the magnitude of this decrease was smaller in patients with MDD than in controls. More...
rostral anterior cingulate cortex (rACC)	Wagner, 2008	patients and normal controls		The relative hyperactivation of the rACC in terms of inabili...... The relative hyperactivation of the rACC in terms of inability to deactivate this region during the Stroop Color-Word Test showed an inverse correlation with grey matter reduction in the orbitofrontal cortex. More...
rostral ACC	Treadway, 2009	patients and normal controls		Depressed patients showed decreased grey matter volume in th...... Depressed patients showed decreased grey matter volume in the rostral ACC as compared to controls. More...
rostral anterior cingulate cortex (rACC)	Eugene, 2010	patients and normal controls		in depressed participants, increased activation in the rostr...... in depressed participants, increased activation in the rostral anterior cingulate cortex (rACC) is associated with inhibition of negative, but not positive, words. These findings indicate that abnormalities in neural function, especially in the rACC, may underlie difficulties experienced by depressed individuals in inhibiting negative thoughts. More...
rostral anterior cingulate (AC)	Saijo, 2010	patients and normal controls		Electroconvulsive therapy decreased D(2) receptor binding in...... Electroconvulsive therapy decreased D(2) receptor binding in the rostral AC in MDD patients responding to ECT. More...
rostral anterior cingulate	Cooney, 2010	patients and normal controls		Neural activity during rumination versus abstract distractio...... Neural activity during rumination versus abstract distraction was greater for depressed than for control participants in the amygdala, rostral anterior cingulate/medial prefrontal cortex, dorsolateral prefrontal cortex, posterior cingulate, and parahippocampus. More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
rostral anterior cingulate cortex		NPY(neuropeptide Y (NPY))	gene	Mickey, 2011	patients and normal controls	P-value<0.05	Whole-brain regression of responses to negative words showed...... Whole-brain regression of responses to negative words showed that the rostral anterior cingulate cortex activated in the low-expression group and deactivated in the high-expression group (P < .05). More...
rostral anterior cingulate gyrus		Glucose(glucose)	molecule	Saxena, 2003	patients only		improvement of major depressive disorder symptoms was signif...... improvement of major depressive disorder symptoms was significantly correlated with higher pretreatment (glucose) metabolism in the medial prefrontal cortex and rostral anterior cingulate gyrus (Talairach coordinates: x=0, y=62, z=10) (z=2.91). More...
rostral ACC		Hydrocortisone(cortisol)	molecule	Treadway, 2009	patients and normal controls		Rostral ACC volume was inversely correlated with both cortis...... Rostral ACC volume was inversely correlated with both cortisol and early adverse events. More...
rostral anterior cingulate cortex (rACC)		Delta wave(delta current density)	neurobiological system	Wacker, 2009	normal people		Anhedonia was correlated with increased resting delta curren...... Anhedonia was correlated with increased resting delta current density (i.e., decreased resting activity) in the rostral anterior cingulate cortex (rACC). More...
rostral anterior cingulate cortex (rACC)		Orbitofrontal cortex(orbitofrontal cortex)	brain morphology and function	Wagner, 2008	patients and normal controls		The relative hyperactivation of the rACC in terms of inabili...... The relative hyperactivation of the rACC in terms of inability to deactivate this region during the Stroop Color-Word Test showed an inverse correlation with grey matter reduction in the orbitofrontal cortex. More...
rostral anterior cingulate		Working memory(working memory (WM))	cognition and behavior	Rose, 2006	patients and normal controls		Therefore, this study implies that the performance of WM tas...... Therefore, this study implies that the performance of WM tasks is associated with a dysfunctional activation of the rostral anterior cingulate cortex in MDD. More...
rostral anterior cingulate cortex (rACC)		Cognitive control(inhibition)	cognition and behavior	Eugene, 2010	patients and normal controls		in depressed participants, increased activation in the rostr...... in depressed participants, increased activation in the rostral anterior cingulate cortex (rACC) is associated with inhibition of negative, but not positive, words. More...
rostral anterior cingulate cortex (rACC)		Anhedonia(anhedonia)	symptoms	Wacker, 2009	normal people		Anhedonia was correlated with increased resting delta curren...... Anhedonia was correlated with increased resting delta current density (i.e., decreased resting activity) in the rostral anterior cingulate cortex (rACC). More...
rostral anterior cingulate cortex (rACC)		Depressed mood(depressive symptoms)	symptoms	Boes, 2008	normal people	14.6% reduction; F = 8.90, P-value = .005	The rACC volume was significantly lower in boys with subclin...... The rACC volume was significantly lower in boys with subclinical depressive symptoms compared with boys with no depressive symptoms, particularly on the left side (14.6% reduction; F = 8.90, p = .005). More...
rostral ACC		Life events(early adverse events)	environment	Treadway, 2009	patients and normal controls		Rostral ACC volume was inversely correlated with both cortis...... Rostral ACC volume was inversely correlated with both cortisol and early adverse events. More...

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Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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