MK4MDD

Cognition and Behavior Report

Basic Information
Name Reward processing
Description "A psychological reward is a process that reinforces behavior - something that, when offered, causes a behavior to increase in intensity. Reward is an operational concept for describing the positive value an individual ascribes to an object, behavioral act or an internal physical state. Natural rewards include those that are necessary for the survival of species, such as eating, drinking, sex, and fighting. Secondary rewards derive their value from the primary reward, and include shelter, money, pleasant touch, beauty, music, etc. The functions of rewards are based directly on the modification of behavior and indirectly on the sensory properties of rewards. For instance, altruism may induce a larger psychological reward, although it doesn't cause sensations. Rewards are generally considered more effective than punishment in enforcing positive behavior. Rewards induce learning, approach behavior and feelings of positive emotions."
No. of Studies (Positive/Negative) 13 (13/0) Help

Positive relationships betweenReward processing and MDD (count: 6)
Name in Literature Reference Research Type Statistical Result Relation Description Help
rewarding effects of dextroamphetamine Cardenas, 2002 patients and normal controls Severity of depression was significantly correlated with inc...... Severity of depression was significantly correlated with increased rewarding effects of d-amph. More...
reduced discrimination of gain versus nongain outcomes Knutson, 2008 patients and normal controls Depressed participants also showed reduced discrimination of...... Depressed participants also showed reduced discrimination of gain versus nongain outcomes. More...
reward-learning Kumar, 2008 patients and normal controls Patients with MDD have blunted temporal difference (TD) rewa...... Patients with MDD have blunted temporal difference (TD) reward-learning signals. More...
reward responsiveness Pizzagalli, 2008 patients and normal controls Compared to controls, MDD subjects showed significantly redu...... Compared to controls, MDD subjects showed significantly reduced reward responsiveness. More...
reward anticipation Olino, 2011 patients and normal controls Depressed youth demonstrated reduced reward anticipation rel...... Depressed youth demonstrated reduced reward anticipation relative to healthy youth. More...
reward processing Robinson, 2012 patients and normal controls Impaired reward (but not punishment) reversal accuracy was f...... Impaired reward (but not punishment) reversal accuracy was found alongside attenuated anteroventral striatal response to unexpected reward in depression. More...

Positive relationships between Reward processing and other level components at different levels (count: 19) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Reward processing in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships betweenReward processing and MDD (count: 0)
Negative relationships between Reward processing and other level components at different levels (count: 0) Help