MK4MDD

Brain Morphology and Function Report

Basic Information
Name subgenual anterior cingulate
Brain Morphology Please reference to the description for Anterior cingulate cortex
No. of Studies (Positive/Negative) 8(8/0) Help

Positive relationships between subgenual anterior cingulate and MDD (count: 8)
Name in Literature Reference Research Type Statistical Result Relation Description Help
subgenual anterior cingulate cortex Neumeister, 2006 patients and normal controls A direct effect of 5-HTTLPR on the regulation of regional ce...... A direct effect of 5-HTTLPR on the regulation of regional cerebral metabolic rates for glucose was identified in patients with rMDD for the amygdala, hippocampus, and subgenual anterior cingulate cortex. More...
subgenual ACC-based neural network Cullen, 2009 patients and normal controls Seed-based connectivity analysis revealed that adolescents w...... Seed-based connectivity analysis revealed that adolescents with MDD have decreased functional connectivity in a subgenual ACC-based neural network that includes the supragenual ACC (BA 32), the right medial frontal cortex (BA 10), the left inferior (BA 47) and superior frontal cortex (BA 22), superior temporal gyrus (BA 22), and the insular cortex (BA 13). More...
subgenual anterior cingulate cortex (ACC) Cullen, 2009 patients and normal controls Seed-based connectivity analysis revealed that adolescents w...... Seed-based connectivity analysis revealed that adolescents with MDD have decreased functional connectivity in a subgenual ACC-based neural network that includes the supragenual ACC (BA 32), the right medial frontal cortex (BA 10), the left inferior (BA 47) and superior frontal cortex (BA 22), superior temporal gyrus (BA 22), and the insular cortex (BA 13). More...
subgenual anterior cingulate Cooney, 2010 patients and normal controls Depressed participants exhibited increased activation in the...... Depressed participants exhibited increased activation in the orbitofrontal cortex, subgenual anterior cingulate, and dorsolateral prefrontal cortex as compared with healthy controls during rumination versus concrete distraction. More...
subgenual anterior cingulate cortex (ACC) Holsen, 2011 patients and normal controls fMRI results showed greater BOLD signal intensity changes in...... fMRI results showed greater BOLD signal intensity changes in controls versus MDD in hypothalamus, amygdala, hippocampus, OFC, ACC, and subgenual ACC, findings unrelated to medication status. More...
subgenual anterior cingulate cortex (sgACC) Tripp, 2011 patients and normal controls SgACC SST was reduced in MDD patients. SgACC SST was reduced in MDD patients.
subgenual anterior cingulate cortex (sACC) Niida, 2011 patients and normal controls sACC volume reduction was noted in 66 of the 71 patients rec...... sACC volume reduction was noted in 66 of the 71 patients receiving treatment of MDD, with sensitivity of 93%, specificity of 85%, and accuracy of 90%.That patients receiving treatment of MDD often showed reduction in sACC volume suggests the usefulness of this parameter as an objective auxiliary means of diagnosis for MDD. More...
subgenual anterior cingulate cortex (sACC) Steiner, 2011 patients and normal controls P-value = 0.003 Depressed patients had a significantly increased density of ...... Depressed patients had a significantly increased density of QUIN-positive cells in the sACC (P = 0.003) compared to controls. More...

Positive relationships between subgenual anterior cingulate and other components at different levels (count: 10) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of subgenual anterior cingulate in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between subgenual anterior cingulate and MDD (count: 0)
Negative relationships between subgenual anterior cingulate and other components at different levels (count: 0) Help