MK4MDD

Molecule Report

Basic Information
Name Progesterone
Description The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
MeSH ID D011374
No. of Studies (Positive/Negative) 2(2/0) Help

Positive relationship between Progesterone and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
progesterone Hardoy, 2006 patients and normal controls Plasma concentrations of progesterone and 3alpha,5alpha-THPR...... Plasma concentrations of progesterone and 3alpha,5alpha-THPROG were significantly greater in patients than in controls, also being higher in BD patients than in MDD patients. More...
progesterone Holsen, 2011 patients and normal controls MDD women had a lower serum estradiol and higher serum proge...... MDD women had a lower serum estradiol and higher serum progesterone compared to controls. More...

Positive relationships between Progesterone and other components at different levels (count: 3) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of Progesterone in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationship between Progesterone and MDD (count: 0)
Negative relationships between Progesterone and other components at different levels (count: 0) Help