Pathway Report

Name	Phosphatidylinositol signalling system
KEGG Link	ID: hsa04070 Name: phosphatidylinositol signaling_system Brief Description: Phosphatidylinositol signaling system Full Description:
No. of Studies (Positive/Negative)	1 (1/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
Phosphatidylinositol signalling system	Kao CF, 2012	patients and normal controls		We found 17 significantly enriched pathways for depression We found 17 significantly enriched pathways for depression

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
ITPR1	inositol 1,4,5-trisphosphate receptor, type 1	Literature-origin; SNP mapped	1(1/0)
PIK3C2G	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma	Literature-origin	1(1/0)
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	Literature-origin	1(1/0)
INPP5A	inositol polyphosphate-5-phosphatase, 40kDa	Literature-origin	1(1/0)
CALM2	calmodulin 2 (phosphorylase kinase, delta)	Literature-origin	1(1/0)
PIK3C2A	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	Literature-origin	1(1/0)
DGKG	diacylglycerol kinase, gamma 90kDa	Literature-origin	1(1/0)
PRKCG	protein kinase C, gamma	SNP mapped	0(0/0)
DGKH	diacylglycerol kinase, eta	Literature-origin	1(1/0)
PRKCB	protein kinase C, beta	Protein mapped	0(0/0)
SYNJ2	synaptojanin 2	Literature-origin	1(1/0)