Brain Morphology and Function Report

Name	Superior temporal gyrus
Brain Morphology	The superior temporal gyrus is one of three (sometimes two) gyri in the temporal lobe of the human brain, which is located laterally to the head, situated somewhat above the external ear.
Brain Function	The superior temporal gyrus has been involved in the perception of emotions in facial stimuli.
Picture	From Wiki.
No. of Studies (Positive/Negative)	9(9/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
superior temporal cortex	Costafreda, 2009	patients and normal controls		Decreased grey matter density in the superior temporal corte...... Decreased grey matter density in the superior temporal cortex (BA 22), showed the highest contribution to the diagnosis of depression. More...
superior temporal gyrus	Canli, 2004	patients and normal controls		For happy words, depressed subjects exhibited less activatio...... For happy words, depressed subjects exhibited less activation than did controls to happy words in fronto-temporal and limbic regions. For sad words, depressed subjects showed more activation than did controls in the inferior parietal lobule and less activation in the superior temporal gyrus and cerebellum More...
superior temporal cortex	Bielau, 2007	patients and normal controls		Post hoc tests demonstrated higher neuronal densities in uni...... Post hoc tests demonstrated higher neuronal densities in unipolar patients compared with bipolar patients and controls in superior temporal cortex More...
superior temporal gyrus	Cullen, 2009	patients and normal controls		Seed-based connectivity analysis revealed that adolescents w...... Seed-based connectivity analysis revealed that adolescents with MDD have decreased functional connectivity in a subgenual ACC-based neural network that includes the supragenual ACC (BA 32), the right medial frontal cortex (BA 10), the left inferior (BA 47) and superior frontal cortex (BA 22), superior temporal gyrus (BA 22), and the insular cortex (BA 13). More...
bilateral caudal superior temporal gyrus (STG)	Takahashi, 2010	patients and normal controls		Both current and remitted MDD patients showed a significant ...... Both current and remitted MDD patients showed a significant volume reduction of the left PT and bilateral caudal STG as compared with healthy controls. More...
superior temporal gyrus	Naismith, 2010	patients and normal controls		control subjects showed significantly greater activity in th...... control subjects showed significantly greater activity in the middle frontal gyrus whereas the patients exhibited greater activity in the superior temporal gyrus More...
superior temporal cortex	Pu, 2011	patients and normal controls		MDD patients showed a smaller increase in lateral prefrontal...... MDD patients showed a smaller increase in lateral prefrontal and superior temporal cortex activation during the 2-back task and associated poorer task performance than healthy controls. More...
middle-superior temporal gyri	Lee, 2011	patients and normal controls		Decreased gray matter concentration was found in MDD patient...... Decreased gray matter concentration was found in MDD patients in the bilateral amygdalae, hippocampi, fusiform gyri, lingual gyri, insular gyri, middle-superior temporal gyri, thalami, cingulate gyri, the central lobule of the cerebellum, and the midbrain encompassing the dorsal raphe nuclei (DRN) More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
superior temporal gyri		rs6438552(rs6438552)	SNP	Inkster, 2009	patients and normal controls	P-value=0.02	Rs6438552, a putative functional intronic SNP that showed 3 ...... Rs6438552, a putative functional intronic SNP that showed 3 significant GM clusters in the right and left superior temporal gyri and the right hippocampus (P < .001, P = .02, and P = .02, respectively, corrected for multiple comparisons across the whole brain). More...
superior temporal gyri		GSK3B(glycogen synthase kinase-3beta (GSK3beta))	gene	Inkster, 2009	patients and normal controls	P-value<0.05	Rs6438552 in this gene showed 3 significant GM clusters in t...... Rs6438552 in this gene showed 3 significant GM clusters in the right and left superior temporal gyri and the right hippocampus (P < .001, P = .02, and P = .02, respectively, corrected for multiple comparisons across the whole brain). More...
superior temporal gyrus		subgenual anterior cingulate(subgenual ACC-based neural network)	brain morphology and function	Cullen, 2009	patients and normal controls		Seed-based connectivity analysis revealed that adolescents w...... Seed-based connectivity analysis revealed that adolescents with MDD have decreased functional connectivity in a subgenual ACC-based neural network that includes the supragenual ACC (BA 32), the right medial frontal cortex (BA 10), the left inferior (BA 47) and superior frontal cortex (BA 22), superior temporal gyrus (BA 22), and the insular cortex (BA 13). More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web