Component A Approved Name (Name in Paper) |
Component A Type |
Component B Approved Name (Name in Paper) |
Component B Type |
Statistical Result |
Relationship Description |
Result Category (Positive/Negative)) |
Attribution and attitude (negativistic dysfunctional attitudes)
|
cognition and behavior |
Sodium-dependent serotonin transporter (serotonin transporter (5-HTT)) |
protein |
P-value<0.01 |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). |
Positive
|
MDD
|
syndrome |
Sodium-dependent serotonin transporter (serotonin transporter (5-HTT)) |
protein |
P-value<0.01 |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). |
Positive
|
Attribution and attitude (negativistic dysfunctional attitudes)
|
cognition and behavior |
Caudate nucleus (caudate) |
brain morphology and function |
r = 0.64-0.74 [P values, .003 to <.001] |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). The magnitude of regional 5-HTT BP can provide a vulnerability to low levels of extracellular serotonin and symptoms of extremely negativistic dysfunctional attitudes. |
Positive
|
Attribution and attitude (negativistic dysfunctional attitudes)
|
cognition and behavior |
Anterior cingulate cortex (anterior cingulate) |
brain morphology and function |
r = 0.64-0.74 [P values, .003 to <.001] |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). The magnitude of regional 5-HTT BP can provide a vulnerability to low levels of extracellular serotonin and symptoms of extremely negativistic dysfunctional attitudes. |
Positive
|
Attribution and attitude (negativistic dysfunctional attitudes)
|
cognition and behavior |
Putamen (putamen) |
brain morphology and function |
r = 0.64-0.74 [P values, .003 to <.001] |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). The magnitude of regional 5-HTT BP can provide a vulnerability to low levels of extracellular serotonin and symptoms of extremely negativistic dysfunctional attitudes. |
Positive
|
Attribution and attitude (negativistic dysfunctional attitudes)
|
cognition and behavior |
Prefrontal cortex (prefrontal cortex) |
brain morphology and function |
r = 0.64-0.74 [P values, .003 to <.001] |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). The magnitude of regional 5-HTT BP can provide a vulnerability to low levels of extracellular serotonin and symptoms of extremely negativistic dysfunctional attitudes. |
Positive
|
Anterior cingulate cortex (anterior cingulate)
|
brain morphology and function |
Sodium-dependent serotonin transporter (serotonin transporter (5-HTT)) |
protein |
P-value<0.01 |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). |
Positive
|
Attribution and attitude (negativistic dysfunctional attitudes)
|
cognition and behavior |
Thalamus (thalamus) |
brain morphology and function |
r = 0.64-0.74 [P values, .003 to <.001] |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). The magnitude of regional 5-HTT BP can provide a vulnerability to low levels of extracellular serotonin and symptoms of extremely negativistic dysfunctional attitudes. |
Positive
|
Prefrontal cortex (prefrontal cortex)
|
brain morphology and function |
Sodium-dependent serotonin transporter (serotonin transporter (5-HTT)) |
protein |
P-value<0.01 |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). |
Positive
|
Caudate nucleus (caudate)
|
brain morphology and function |
Sodium-dependent serotonin transporter (serotonin transporter (5-HTT)) |
protein |
P-value<0.01 |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). |
Positive
|
Thalamus (thalamus)
|
brain morphology and function |
Sodium-dependent serotonin transporter (serotonin transporter (5-HTT)) |
protein |
P-value<0.01 |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). |
Positive
|
Putamen (putamen)
|
brain morphology and function |
Sodium-dependent serotonin transporter (serotonin transporter (5-HTT)) |
protein |
P-value<0.01 |
In the MDE(major depressive episodes) subjects, increased 5-HTT BP was strongly associated with more negativistic dysfunctional attitudes in brain regions primarily sampling serotonergic nerve terminals (prefrontal cortex, anterior cingulate, thalamus, caudate, and putamen; r = 0.64-0.74 [P values, .003 to <.001]). |
Positive
|