Reactome Pathway Report
Basic Information
| ID |
|
| Name |
mrna splicing_minor_pathway
|
| Description |
The splicing of a subset of pre-mRNA introns occurs by a second pathway, designated the AT-AC or U12-dependent splicing pathway. AT-AC introns have highly conserved, non-canonical splice sites that are removed by the AT-AC spliceosome, which contains distinct snRNAs (U11, U12, U4atac, U6atac) that are structurally and functionally analogous to the major spliceosome. U5 snRNA as well as many of the protein factors appear to be conserved between the two spliceosomes.
|
REACT_1753 related genes in MK4MDD (count: 3)
| Approved Symbol |
Approved Name |
Type |
No. of Studies (Positive/Negative) |
| DDX23 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 |
Literature-origin
|
1(1/0) |
| SF3B3 |
splicing factor 3b, subunit 3, 130kDa |
Literature-origin
|
1(1/0) |
| SNRPE |
small nuclear ribonucleoprotein polypeptide E |
Literature-origin
|
1(1/0) |
