Pathway Report

Name	wnt receptor signaling pathway
GO Link	ID: GO:0016055 Name: Wnt receptor signaling pathway Type: biological process
Description	biological_process. The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.[GOC:dph, GOC:go_curators, PMID:11532397]
No. of Studies (Positive/Negative)	1 (1/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
Wnt pathway	Inkster, 2010	patients and normal controls		We observed associations for polymorphisms in 8/13 canonical...... We observed associations for polymorphisms in 8/13 canonical Wnt pathway genes More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
LRP4	low density lipoprotein receptor-related protein 4	Literature-origin	1(1/0)
RYK	receptor-like tyrosine kinase	Literature-origin	1(1/0)
SOSTDC1	sclerostin domain containing 1	Literature-origin	1(1/0)
PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A	Literature-origin	1(1/0)
DRD2	dopamine receptor D2	Literature-origin; Protein mapped	4(3/1)