Brain Morphology and Function Report

Name	right insula
Brain Morphology	Please reference to the description for Insula
No. of Studies (Positive/Negative)	5(5/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
right insula	Beauregard, 2006	patients and normal controls		there was greater activation in the right insula in depresse...... there was greater activation in the right insula in depressed individuals More...
right insula	Lee, 2007	patients and normal controls		Depressed individuals demonstrated lower activity in the rig...... Depressed individuals demonstrated lower activity in the right insula to negative affective pictures. More...
right insula	Yao, 2009	patients and normal controls	P-value < 0.005, uncorrected	Compared with healthy controls, decreased ReHo (regional hom...... Compared with healthy controls, decreased ReHo (regional homogeneity) were found in depressed patients in the right insula (p<0.005, uncorrected). More...
right insula	Liu, 2010	patients and high-risk people and normal controls		Compared with the control group, subjects with MDD and those...... Compared with the control group, subjects with MDD and those at high risk for MDD exhibited significantly decreased ReHo in the right insula and in the left cerebellum. More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
right insula		gamma-Aminobutyric Acid receptor(GABA(A)-benzodiazepine receptor)	molecule	Klumpers, 2010	patients and normal controls		Plasma GABA did not discriminate MDD from controls, but corr...... Plasma GABA did not discriminate MDD from controls, but correlated inversely with [(11)C]FMZ binding in the right insula. More...
right insula		Increased agitation(anxiety)	symptoms	Yao, 2009	patients and normal controls		Anxiety severity was positively correlated with the ReHo in ...... Anxiety severity was positively correlated with the ReHo in the right insula. More...
right insula		Feelings of hopelessness, worthlessness, and guilt(hopelessness)	symptoms	Yao, 2009	patients and normal controls		Hopelessness severity was positively correlated with the ReH...... Hopelessness severity was positively correlated with the ReHo (regional homogeneity) in the right ventral anterior cingulate gyrus and the right insula. More...
right insula		Low energy(retardation)	symptoms	Yao, 2009	patients and normal controls		Retardation severity was positively correlated with the ReHo...... Retardation severity was positively correlated with the ReHo (regional homogeneity) in the right posterior cingulate gyrus and the right insula. More...

---

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web