Pathway Report

Name	metabolic process
GO Link	ID: GO:0008152 Name: metabolic process Type: biological process
Description	biological_process. The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.[GOC:go_curators, ISBN:0198547684]
No. of Studies (Positive/Negative)	1 (1/0)

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
Metabolic process		SLC17A7(vesicular glutamate transporter 1 (VGLUT1))	gene	Tordera RM, 2011	animal model		genes invovled in this pathwy were regulated in frontal cort...... genes invovled in this pathwy were regulated in frontal cortex of VGLUT1(+/-) mice More...
Metabolic process		Stress(stress)	environment	Tordera RM, 2011	animal model		After CMS, Specifically, a dowregulation in genes that promo...... After CMS, Specifically, a dowregulation in genes that promote cell proliferation (Anapc7), cell growth (CsnK1g1), cell survival (Hdac3), and inhibition of apoptosis (Dido1) was observed. Genes linked to cytoskeleton (Hspg2, Invs), psychiatric disorders (Grin1, MapK12) or an antioxidant enzyme (Gpx2) were also downregulated. Moreover, genes that inhibit the MAPK pathways (Dusp14), stimulate oxidative metabolism (Eif4a2) and enhance glutamate transmission (Rab8b) were upregulated. More...

---

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web