Brain Morphology and Function Report

Name	medial orbitofrontal cortex
Brain Morphology	Please reference to the description for Orbitofrontal cortex
No. of Studies (Positive/Negative)	5(5/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
medial orbitofrontal cortex	Liotti, 2002	patients and normal controls		Mood provocation in both depressed groups resulted in region...... Mood provocation in both depressed groups resulted in regional cerebral blood flow (rCBF) decreases in medial orbitofrontal cortex Brodmann's area 10/11, which were absent in the healthy group. More...
medial orbitofrontal cortex	Rose, 2006	patients and normal controls	cluster size (K(E))/volume = 128/1024 mm3, corrected P-value = 0.025	Random effects analysis of the functional imaging data revea...... Random effects analysis of the functional imaging data revealed a significant difference in load-dependent activation in the medial orbitofrontal cortex between patients and controls. While both participant groups exhibited a significant decrease in activation in this region with increased task difficulty, the magnitude of this decrease was smaller in patients with MDD than in controls. More...
medial orbitofrontal cortex (OFC)	Lee, 2008	patients and normal controls		When shown pictures of sad faces, patients with MDD relative...... When shown pictures of sad faces, patients with MDD relative controls showed decreased activations bilaterally in the medial OFC. We also found significant group differences under the angry face condition, bilaterally, in the medial OFC areas. More...
medial orbitofrontal cortex	Desseilles, 2009	patients and normal controls		Analyses of fMRI data revealed that MDD patients show a hype...... Analyses of fMRI data revealed that MDD patients show a hyperactivity in subgenual cingulate/medial orbitofrontal cortex that was modulated by attentional load. More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
medial orbitofrontal cortex		Functional connectivity(functional connectivity (FC) involved in emotional regulation)	brain morphology and function	Zhou, 2010	patients and normal controls		In the TNN (task-negative networks), the increased FCs were ...... In the TNN (task-negative networks), the increased FCs were primarily located in the posterior cingulate cortex and the medial orbitofrontal cortex, which are involved in episodic memory, self-reflection and emotional regulation. More...
medial orbitofrontal cortex		Functional connectivity(functional connectivity (FC) involved in episodic memory)	brain morphology and function	Zhou, 2010	patients and normal controls		In the TNN (task-negative networks), the increased FCs were ...... In the TNN (task-negative networks), the increased FCs were primarily located in the posterior cingulate cortex and the medial orbitofrontal cortex, which are involved in episodic memory, self-reflection and emotional regulation. More...
medial orbitofrontal cortex		Functional connectivity(functional connectivity (FC) involved in self-reflection)	brain morphology and function	Zhou, 2010	patients and normal controls		In the TNN (task-negative networks), the increased FCs were ...... In the TNN (task-negative networks), the increased FCs were primarily located in the posterior cingulate cortex and the medial orbitofrontal cortex, which are involved in episodic memory, self-reflection and emotional regulation. More...
medial orbitofrontal cortex		Working memory(working memory (WM))	cognition and behavior	Rose, 2006	patients and normal controls		Therefore, this study implies that the performance of WM tas...... Therefore, this study implies that the performance of WM tasks is associated with a dysfunctional activation of the medial orbitofrontal in MDD. More...
medial orbitofrontal cortex		Attention(attention)	cognition and behavior	Desseilles, 2009	patients and normal controls		Analyses of fMRI data revealed that MDD patients show a hype...... Analyses of fMRI data revealed that MDD patients show a hyperactivity in subgenual cingulate/medial orbitofrontal cortex that was modulated by attentional load. More...
medial orbitofrontal cortex		Depressed mood(depressed mood)	symptoms	Liotti, 2002	patients and normal controls		Mood provocation in both depressed groups resulted in region...... Mood provocation in both depressed groups resulted in regional cerebral blood flow (rCBF) decreases in medial orbitofrontal cortex Brodmann's area 10/11, which were absent in the healthy group. More...

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Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

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