Brain Morphology and Function Report

Name	left insula
Brain Morphology	Please reference to the description for Insula
No. of Studies (Positive/Negative)	6(6/0)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
left insula	Lee, 2007	patients and normal controls		Depressed individuals showed lower activity in the left insu...... Depressed individuals showed lower activity in the left insula to positive pictures. More...
left insula	Liu, 2010	patients and normal controls	P-value < 0.01	Fractional anisotropy (FA) values in the MD group were signi...... Fractional anisotropy (FA) values in the MD group were significantly lower than those of the healthy controls in the white matter of the left insula (P<0.01). More...
left insula	Surguladze, 2010	patients and normal controls		Compared with healthy controls, patients with depression dem...... Compared with healthy controls, patients with depression demonstrated greater activation in left insula to expressions of strong disgust. More...
left insula	Gotlib, 2010	high-risk people and normal controls		high-risk participants showed less activation than did their...... high-risk participants showed less activation than did their low-risk counterparts in the left insula More...
left insula	Soriano-Mas, 2011	patients and normal controls		Melancholic patients showed gray matter reductions in the le...... Melancholic patients showed gray matter reductions in the left insula and white matter increases in the upper brainstem tegmentum. More...
left insula	Pan, 2011	patients and normal controls	P-value = .004	and that NATs (adolescents with a history of depressive diso...... and that NATs (adolescents with a history of depressive disorder but no suicide attempt), but not ATTs (adolescent suicide attempters with a history of major depressive disorder), showed significantly greater activity than HCs(healthy controls) in the left insula (p = .004) to go-no-go response inhibition blocks More...

Name in Literature	Related Components
	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description	All
left insula		Depressed mood(depression)	symptoms	Lee, 2007	patients and normal controls		Within the MDD group, the severity of depression correlated ...... Within the MDD group, the severity of depression correlated with the activity of the left insula to negative pictures. More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web