Brain Morphology and Function Report

Basic Information

Name	anterior hippocampus
Brain Morphology	Please reference to the description for Hippocampus
No. of Studies (Positive/Negative)	3(2/1)

Positive relationships between anterior hippocampus and MDD (count: 2)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
anterior hippocampal regions	Lau, 2010	patients and normal controls	F's>4, p's<0.05	Significant effects of diagnosis and diagnosis-by-genotype i...... Significant effects of diagnosis and diagnosis-by-genotype interactions (F's>4, p's<0.05) characterized activations in amygdala and anterior hippocampal regions. Greater activations in patients than healthy adolescents were found. More...
anterior hippocampus	Cornwell, 2010	patients and normal controls		Robust group differences in theta activity were observed in ...... Robust group differences in theta activity were observed in right medial temporal cortices during navigation, with patients exhibiting less engagement of the anterior hippocampus and parahippocampal cortices relative to comparison subjects. More...

Positive relationships between anterior hippocampus and other components at different levels (count: 2)

Genetic/epigenetic locus					Protein and other molecule			Cell and molecular pathway			Neural system			Cognition and behavior		Symptoms and signs			Environment

Name in Literature	Level	Approved Name(Name in Literature)	Type	Reference	Research Type	Statistical Result	Relation Description
Name in Literature	Related Components
anterior hippocampal regions		BDNF(Brain Derived Neurotrophic Factor (BDNF))	gene	Lau, 2010	patients and normal controls	P-value<0.05	Significant effects of diagnosis and diagnosis-by-genotype i...... Significant effects of diagnosis and diagnosis-by-genotype interactions (F's>4, p's<0.05) characterized activations in amygdala and anterior hippocampal regions. Greater activations in patients than healthy adolescents were found. Critically, these hyperactivations were modulated by BDNF genotype: Met-carriers showed greater neural responses of emotional faces than Val/Val homozygotes in patients only. More...
anterior hippocampus		Perception(impaired spatial navigation)	cognition and behavior	Cornwell, 2010	patients and normal controls		Depressed patients showed impaired spatial navigation. Dysfu...... Depressed patients showed impaired spatial navigation. Dysfunction of right anterior hippocampus and parahippocampal cortices may underlie this deficit and stem from structural abnormalities commonly found in depressed patients. More...

Positive relationship network of anterior hippocampus in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between anterior hippocampus and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
anterior hippocampal volume	Neumeister, 2005	patients and normal controls		Anterior hippocampal volume did not differ between patients ...... Anterior hippocampal volume did not differ between patients and controls. More...

Negative relationships between anterior hippocampus and other components at different levels (count: 0)